Cholesterol biosynthesis
Song BL, Javitt NB, DeBose-Boyd RA. Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol. Cell Metab. 2005 Mar;1(3):179–89. doi: 10.1016/j.cmet.2005.01.001. PMID: 16054061.; Herman GE. Disorders of cholesterol biosynthesis: prototypic metabolic malformation syndromes. Hum Mol Genet. 2003 Apr 01;12 Spec No 1():R75–88. doi: 10.1093/hmg/ddg072. PMID: 12668600.; Gaylor JL. Membrane-Bound Enzymes of Cholesterol Synthesis from Lanosterol. Biochemical and Biophysical Research Communications. 2002 Apr;292(5):1139–46. doi: 10.1006/bbrc.2001.2008.; Russell DW. Cholesterol biosynthesis and metabolism. Cardiovasc Drugs Ther. 1992 Apr;6(2):103–10. doi: 10.1007/bf00054556. PMID: 1390320.; Rudney H, Sexton RC. Regulation of cholesterol biosynthesis. Annu Rev Nutr. 1986;6():245–72. doi: 10.1146/annurev.nu.06.070186.001333. PMID: 3524618.
Metabolites
4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
Formula: C29H46O (410.3548466)
CAS ID: 64284-64-6
Enzyme
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Proteins
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