SARS-CoV-1 activates/modulates innate immune responses
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Seminars in Immunopathology. 2017 May 02;39(5):529–39. doi: 10.1007/s00281-017-0629-x.; Hu Y, Li W, Gao T, Cui Y, Jin Y, Li P, Ma Q, Liu X, Cao C. The Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Inhibits Type I Interferon Production by Interfering with TRIM25-Mediated RIG-I Ubiquitination. J Virol. 2017 Apr 15;91(8). PMID: 28148787; PMCID: PMC5375661.; Li SW, Wang CY, Jou YJ, Huang SH, Hsiao LH, Wan L, Lin YJ, Kung SH, Lin CW. SARS Coronavirus Papain-Like Protease Inhibits the TLR7 Signaling Pathway through Removing Lys63-Linked Polyubiquitination of TRAF3 and TRAF6. Int J Mol Sci. 2016 May 05;17(5). PMID: 27164085; PMCID: PMC4881504.; Kindler E, Thiel V, Weber F. Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response. Adv Virus Res. 2016;96():219–43. PMID: 27712625; PMCID: PMC7112302.; Taylor JK, Coleman CM, Postel S, Sisk JM, Bernbaum JG, Venkataraman T, Sundberg EJ, Frieman MB. Severe Acute Respiratory Syndrome Coronavirus ORF7a Inhibits Bone Marrow Stromal Antigen 2 Virion Tethering through a Novel Mechanism of Glycosylation Interference. J Virol. 2015 Dec;89(23):11820–33. PMID: 26378163; PMCID: PMC4645327.; Nieto-Torres JL, Verdiá-Báguena C, Jimenez-Guardeño JM, Regla-Nava JA, Castaño-Rodriguez C, Fernandez-Delgado R, Torres J, Aguilella VM, Enjuanes L. Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome. Virology. 2015 Nov;485():330–9. PMID: 26331680; PMCID: PMC4619128.; Menachery VD, Yount BL, Josset L, Gralinski LE, Scobey T, Agnihothram S, Katze MG, Baric RS. Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity. J Virol. 2014 Apr;88(8):4251–64. PMID: 24478444; PMCID: PMC3993736.; Chen X, Yang X, Zheng Y, Yang Y, Xing Y, Chen Z. SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex. Protein & Cell. 2014 Mar 14;5(5):369–81. doi: 10.1007/s13238-014-0026-3.; Siu K, Chan C, Kok K, Chiu-Yat Woo P, Jin D. Suppression of innate antiviral response by severe acute respiratory syndrome coronavirus M protein is mediated through the first transmembrane domain. Cellular & Molecular Immunology. 2014 Feb 10;11(2):141–9. doi: 10.1038/cmi.2013.61.; Li Y, Chen M, Cao H, Zhu Y, Zheng J, Zhou H. Extraordinary GU-rich single-strand RNA identified from SARS coronavirus contributes an excessive innate immune response. Microbes and Infection. 2013 Feb;15(2):88–95. doi: 10.1016/j.micinf.2012.10.008.; Totura AL, Baric RS. SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon. Current Opinion in Virology. 2012 Jun;2(3):264–75. doi: 10.1016/j.coviro.2012.04.004.; Sun L, Xing Y, Chen X, Zheng Y, Yang Y, Nichols DB, Clementz MA, Banach BS, Li K, Baker SC, Chen Z. Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling. PLoS ONE. 2012 Feb 01;7(2):e30802. doi: 10.1371/journal.pone.0030802.; Varshney B, Agnihothram S, Tan Y, Baric R, Lal SK. Correction: SARS Coronavirus 3b Accessory Protein Modulates Transcriptional Activity of RUNX1b. PLoS ONE. 2012 Mar 07;7(3). doi: 10.1371/annotation/64ae6047-0f9b-4d17-a065-e08c153aa435.; Pfefferle S, Schöpf J, Kögl M, Friedel CC, Müller MA, Carbajo-Lozoya J, Stellberger T, von Dall’Armi E, Herzog P, Kallies S, Niemeyer D, Ditt V, Kuri T, Züst R, Pumpor K, Hilgenfeld R, Schwarz F, Zimmer R, Steffen I, Weber F, Thiel V, Herrler G, Thiel H, Schwegmann-Weßels C, Pöhlmann S, Haas J, Drosten C, von Brunn A. The SARS-Coronavirus-Host Interactome: Identification of Cyclophilins as Target for Pan-Coronavirus Inhibitors. PLoS Pathog. 2011 Oct 27;7(10):e1002331. doi: 10.1371/journal.ppat.1002331.; Chen Y, Su C, Ke M, Jin X, Xu L, Zhang Z, Wu A, Sun Y, Yang Z, Tien P, Ahola T, Liang Y, Liu X, Guo D. Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2'-O-Methylation by nsp16/nsp10 Protein Complex. PLoS Pathog. 2011 Oct 13;7(10):e1002294. doi: 10.1371/journal.ppat.1002294.; Daffis S, Szretter KJ, Schriewer J, Li J, Youn S, Errett J, Lin TY, Schneller S, Zust R, Dong H, Thiel V, Sen GC, Fensterl V, Klimstra WB, Pierson TC, Buller RM, Gale M, Shi PY, Diamond MS. 2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members. Nature. 2010 Nov 18;468(7322):452–6. PMID: 21085181; PMCID: PMC3058805.; Frieman M, Ratia K, Johnston RE, Mesecar AD, Baric RS. Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-kappaB signaling. J Virol. 2009 Jul;83(13):6689–705. PMID: 19369340; PMCID: PMC2698564.; Siu K, Kok K, Ng MJ, Poon VKM, Yuen K, Zheng B, Jin D. Severe Acute Respiratory Syndrome Coronavirus M Protein Inhibits Type I Interferon Production by Impeding the Formation of TRAF3·TANK·TBK1/IKK? Complex. Journal of Biological Chemistry. 2009 Jun;284(24):16202–9. doi: 10.1074/jbc.m109.008227.; Chen Y, Cai H, Pan J, Xiang N, Tien P, Ahola T, Guo D. Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase. Proc Natl Acad Sci U S A. 2009 Mar 03;106(9):3484–9. PMID: 19208801; PMCID: PMC2651275.; Knoops K, Kikkert M, Worm SHEVD, Zevenhoven-Dobbe JC, van der Meer Y, Koster AJ, Mommaas AM, Snijder EJ. SARS-Coronavirus Replication Is Supported by a Reticulovesicular Network of Modified Endoplasmic Reticulum. PLoS Biol. 2008 Sep 16;6(9):e226. doi: 10.1371/journal.pbio.0060226.; Stertz S, Reichelt M, Spiegel M, Kuri T, Martínez-Sobrido L, García-Sastre A, Weber F, Kochs G. The intracellular sites of early replication and budding of SARS-coronavirus. Virology. 2007 May 10;361(2):304–15. PMID: 17210170; PMCID: PMC7103305.; Law AH, Lee DC, Cheung BK, Yim HC, Lau AS. Role for nonstructural protein 1 of severe acute respiratory syndrome coronavirus in chemokine dysregulation. J Virol. 2007 Jan;81(1):416–22. PMID: 17035307; PMCID: PMC1797241.; Kopecky-Bromberg SA, Martínez-Sobrido L, Frieman M, Baric RA, Palese P. Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists. J Virol. 2007 Jan;81(2):548–57. PMID: 17108024; PMCID: PMC1797484.; Cervantes-Barragan L, Züst R, Weber F, Spiegel M, Lang KS, Akira S, Thiel V, Ludewig B. Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon. Blood. 2007 Feb 01;109(3):1131–7. PMID: 16985170; PMCID: PMC8254533.; Bhardwaj K, Sun J, Holzenburg A, Guarino LA, Kao CC. RNA Recognition and Cleavage by the SARS Coronavirus Endoribonuclease. Journal of Molecular Biology. 2006 Aug;361(2):243–56. doi: 10.1016/j.jmb.2006.06.021.; Ricagno S, Egloff MP, Ulferts R, Coutard B, Nurizzo D, Campanacci V, Cambillau C, Ziebuhr J, Canard B. Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family. Proc Natl Acad Sci U S A. 2006 Aug 08;103(32):11892–7. PMID: 16882730; PMCID: PMC2131687.; Lindner HA, Fotouhi-Ardakani N, Lytvyn V, Lachance P, Sulea T, Me´nard R. The Papain-Like Protease from the Severe Acute Respiratory Syndrome Coronavirus Is a Deubiquitinating Enzyme. J Virol. 2005 Dec 15;79(24):15199–208. doi: 10.1128/jvi.79.24.15199-15208.2005.