Miconazole (BioCAD00000026285)

blood urine

Metabolite Card

Formula: C18H14Cl4N2O (413.986)
SMILES: ClC1=CC(Cl)=C(COC(CN2C=CN=C2)C2=C(Cl)C=C(Cl)C=C2)C=C1

Synonyms [en]

miconazole; Miconazole Nitrate; imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI); 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole; Miconazole (Monistat); Miconasil Nitrate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Miconazole. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000026285). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Miconazole is only found in individuals that have used or taken this drug. It is an imidazole antifungal agent that is used topically and by intravenous infusion. [PubChem]Miconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Miconazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis.

Cytoplasm Membrane
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 22916-47-8
  • CAS Registry Number: 47447-52-9
  • CAS Registry Number: 47447-53-0
  • CAS Registry Number: 75319-47-0
  • PubChem: 4189
  • ChEBI: ChEBI:6923
  • ChEBI: ChEBI:82892
  • HMDB: HMDB0015242
  • KEGG: C07223
  • KEGG: C08070
  • KEGG: D00416
  • BioCyc: CPD-4501
  • NCBI MeSH: Miconazole
  • Wikipedia: Miconazole
  • DrugBank: DB01110
  • RefMet: RM0200855
  • MoNA: Alkaloids000042
  • MoNA: AU270602
  • MoNA: AU270603
  • MoNA: AU270604
  • MoNA: AU270605
  • MoNA: AU270606
  • MoNA: CCMSLIB00000078506
  • MoNA: SM860201
  • MoNA: TOF_alkaloids_pos000037
  • Metlin: METLIN_1283
  • Coconut NaturalProduct: CNP0194606.1
  • Coconut NaturalProduct: CNP0194606.2

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
BioCyc:META_PWY-5469 sesamin biosynthesis
BioCyc:META_PWY-5660 taxol biosynthesis
BioCyc:META_PWY-6074 zymosterol biosynthesis
BioCyc:HUMAN_PWY66-5 superpathway of cholesterol biosynthesis
BioCyc:HUMAN_PWY66-341 cholesterol biosynthesis I
BioCyc:META_PWY-5048 rosmarinic acid biosynthesis I
BioCyc:META_PWY-5071 superpathway of rosmarinic acid biosynthesis
BioCyc:HUMAN_PWY66-4 cholesterol biosynthesis III (via desmosterol)
PlantCyc:PLANT_PWY-5469 sesamin biosynthesis
PlantCyc:PLANT_PWY-5048 rosmarinic acid biosynthesis I
PlantCyc:PLANT_PWY-5071 superpathway of rosmarinic acid biosynthesis
View All Pathways