PQQ (BioCAD00000016559)
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Metabolite Card
Formula: C14H6N2O8 (330.0124)
SMILES: OC(=O)C1=CC2=C(N1)C1=C(N=C(C=C1C(O)=O)C(O)=O)C(=O)C2=O
Synonyms [en]
PQQ; pyrroloquinoline quinone; Pyrrolo-quinoline quinone; methoxatin; Coenzyme pqq; Pyrroloquinoline-quinone
Last reviewed on 2024-06-28.
Cite this Page
PQQ. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000016559). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Enzymes containing PQQ are called quinoproteins. PQQ and quinoproteins play a role in the redox metabolism and structural integrity of cells and tissues [PMID:2558842]. It was reported that aminoadipate semialdehyde dehydrogenase (AASDH) might also use PQQ as a cofactor, suggesting a possibility that PQQ is a vitamin in mammals. [PMID:12712191].
DBLinks
- CAS Registry Number: 72909-34-3
- PubChem CID: 1024
- ChEBI: 18315
- HMDB: HMDB0013636
- LipidMaps:
- KEGG: C00113
- BioCyc:
- NCBI MeSH: PQQ Cofactor
- Wikipedia: Pyrroloquinoline_quinone
Other DBLinks
- CAS Registry Number: 72909-34-3
- PubChem: 1024
- ChEBI: ChEBI:18315
- HMDB: HMDB0013636
- HMDB: HMDB13636
- KEGG: C00113
- NCBI MeSH: PQQ Cofactor
- Wikipedia: Pyrroloquinoline_quinone
- DrugBank: DB03205
- Metlin: METLIN_63125
- Coconut NaturalProduct: CNP0253018.0
Class / Ontology
- WishartLab ClassyFire: [Pyrroloquinolines] Pyrroloquinolines
- ChEBI: [CHEBI:18315] pyrroloquinoline quinone
- Coconut NaturalProduct: [Pyridine alkaloids] Pyridine alkaloids
| ID | EC Number | Name |
|---|---|---|
| KEGG:R01019 | 1.2.5.2 | acetaldehyde:pyrroloquinoline-quinone oxidoreductase |
| KEGG:R01873 | 1.1.5.8 | quinate:pyrroloquinoline-quinone 3-oxidoreductase; |
| KEGG:R02415 | 1.1.5.8 | shikimate:pyrroloquinoline-quinone 3-oxidoreductase |
| KEGG:R03535 | 1.2.5.2 | C01359 + C00804<=>C05985 + C00113 + C00001 |
| KEGG:R05120 | C06145 + C00113 + C00001<=>C06144 + C01359 | |
| KEGG:R05121 | C06145 + C01359<=>C06146 + C00113 | |
| KEGG:R07353 | 1.3.3.11 | 6-(2-amino-2-carboxyethyl)-7,8-dioxo-7,8-dihydroquinoline-2,4-dicarboxylate:oxygen oxidoreductase (cyclizing) |
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| BioCyc:TRYPANO_QUINATEDEG-PWY | quinate degradation I |
| BioCyc:TRYPANO_SHIKIMATEDEG-PWY | shikimate degradation I |
| Reactome:R-BTA-1430728 | Metabolism |
| Reactome:R-BTA-71291 | Amino acid and derivative metabolism |
| Reactome:R-CFA-1430728 | Metabolism |
| Reactome:R-DRE-71291 | Amino acid and derivative metabolism |
| Reactome:R-DME-209776 | Metabolism of amine-derived hormones |
| Reactome:R-HSA-209905 | Catecholamine biosynthesis |
| Reactome:R-MMU-1430728 | Metabolism |
| Reactome:R-MMU-209905 | Catecholamine biosynthesis |
| Reactome:R-RNO-209905 | Catecholamine biosynthesis |
| Reactome:R-SSC-209905 | Catecholamine biosynthesis |
| Reactome:R-BTA-209905 | Catecholamine biosynthesis |
| Reactome:R-CFA-71291 | Amino acid and derivative metabolism |
| Reactome:R-DRE-209905 | Catecholamine biosynthesis |
| Reactome:R-DME-1430728 | Metabolism |
| Reactome:R-DME-71291 | Amino acid and derivative metabolism |
| Reactome:R-GGA-71291 | Amino acid and derivative metabolism |
| Reactome:R-HSA-209776 | Metabolism of amine-derived hormones |
| Reactome:R-MMU-209776 | Metabolism of amine-derived hormones |