EC: 3.6.1.6
nucleoside diphosphate phosphatase (nucleoside-diphosphate phosphohydrolase)
| enzyme | lambda | metabolic reaction | experiment |
|---|---|---|---|
| uniprot:Q8K4Y7 [Ca2+] UDP + H2O -> Phosphate + UMP |
(( (Vmax * S) ) / (Km + S)) |
buffer: 50 mM HEPES PH: 7 Temperature: 36 |
Pathways
| pathway id | name |
|---|---|
| BioCyc:HUMAN_PWY-7185 | UTP and CTP dephosphorylation I |
| Reactome:R-HSA-9660826 | Purinergic signaling in leishmaniasis infection |
| Reactome:R-HSA-9664424 | Cell recruitment (pro-inflammatory response) |
| Reactome:R-HSA-9658195 | Leishmania infection |
| Reactome:R-HSA-9824443 | Parasitic Infection Pathways |
| Reactome:R-HSA-1643685 | Disease |
| Reactome:R-MMU-1430728 | Metabolism |
| Reactome:R-CEL-15869 | Nucleotide metabolism |
| Reactome:R-CEL-8956319 | Nucleotide catabolism |
| Reactome:R-CEL-8850843 | Phosphate bond hydrolysis by NTPDase proteins |
| Reactome:R-RNO-1430728 | Metabolism |
| Reactome:R-CEL-1430728 | Metabolism |
| Reactome:R-HSA-1430728 | Metabolism |
| Reactome:R-HSA-15869 | Nucleotide metabolism |
| Reactome:R-HSA-8956319 | Nucleotide catabolism |
| Reactome:R-HSA-8850843 | Phosphate bond hydrolysis by NTPDase proteins |
| Reactome:R-HSA-5663205 | Infectious disease |
| Reactome:R-MMU-15869 | Nucleotide metabolism |
| Reactome:R-MMU-8956319 | Nucleotide catabolism |
| Reactome:R-MMU-8850843 | Phosphate bond hydrolysis by NTPDase proteins |
| Reactome:R-RNO-15869 | Nucleotide metabolism |
| Reactome:R-RNO-8956319 | Nucleotide catabolism |
| Reactome:R-RNO-8850843 | Phosphate bond hydrolysis by NTPDase proteins |
| PathBank:SMP0120670 | Adenylosuccinate Lyase Deficiency |
| PathBank:SMP0000444 | Lactose Synthesis |
| PathBank:SMP0000167 | Adenylosuccinate Lyase Deficiency |
| PathBank:SMP0000220 | Xanthine Dehydrogenase Deficiency (Xanthinuria) |
| PathBank:SMP0000178 | Dihydropyrimidinase Deficiency |
| PathBank:SMP0000512 | Xanthinuria Type I |
| PathBank:SMP0000536 | Mitochondrial DNA Depletion Syndrome-3 |
| PathBank:SMP0000580 | GLUT-1 Deficiency Syndrome |
| PathBank:SMP0063634 | Lactose Synthesis |
| PathBank:SMP0120669 | Adenosine Deaminase Deficiency |
| PathBank:SMP0120673 | AICA-Ribosiduria |
| PathBank:SMP0120709 | Gout or Kelley-Seegmiller Syndrome |
| PathBank:SMP0120717 | Xanthine Dehydrogenase Deficiency (Xanthinuria) |
| PathBank:SMP0120797 | Xanthinuria Type II |
| PathBank:SMP0120821 | Myoadenylate Deaminase Deficiency |
| PathBank:SMP0120507 | UMP Synthase Deficiency (Orotic Aciduria) |
| PathBank:SMP0120644 | GLUT-1 Deficiency Syndrome |
| PathBank:SMP0000046 | Pyrimidine Metabolism |
| PathBank:SMP0000050 | Purine Metabolism |
| PathBank:SMP0000144 | Adenosine Deaminase Deficiency |
| PathBank:SMP0000203 | Molybdenum Cofactor Deficiency |
| PathBank:SMP0000219 | UMP Synthase Deficiency (Orotic Aciduria) |
| PathBank:SMP0000428 | Mercaptopurine Action Pathway |
| PathBank:SMP0000535 | Adenine Phosphoribosyltransferase Deficiency (APRT) |
| PathBank:SMP0000579 | Congenital Disorder of Glycosylation CDG-IId |
| PathBank:SMP0087473 | Pyrimidine Metabolism |
| PathBank:SMP0120728 | Lesch-Nyhan Syndrome (LNS) |
| PathBank:SMP0120752 | Molybdenum Cofactor Deficiency |
| PathBank:SMP0120756 | Purine Nucleoside Phosphorylase Deficiency |
| PathBank:SMP0120796 | Xanthinuria Type I |
| PathBank:SMP0120820 | Mitochondrial DNA Depletion Syndrome |
| PathBank:SMP0120473 | Dihydropyrimidinase Deficiency |
| PathBank:SMP0000365 | Gout or Kelley-Seegmiller Syndrome |
| PathBank:SMP0000210 | Purine Nucleoside Phosphorylase Deficiency |
| PathBank:SMP0000202 | MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy) |
| PathBank:SMP0000430 | Thioguanine Action Pathway |
| PathBank:SMP0000513 | Xanthinuria Type II |
| PathBank:SMP0000537 | Myoadenylate Deaminase Deficiency |
| PathBank:SMP0087332 | Purine Metabolism |
| PathBank:SMP0087448 | Lactose Synthesis |
| PathBank:SMP0063658 | Pyrimidine Metabolism |
| PathBank:SMP0120819 | Adenine Phosphoribosyltransferase Deficiency (APRT) |
| PathBank:SMP0120458 | beta-Ureidopropionase Deficiency |
| PathBank:SMP0120530 | MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy) |
| PathBank:SMP0120643 | Congenital Disorder of Glycosylation CDG-IId |
| PathBank:SMP0000364 | Lesch-Nyhan Syndrome (LNS) |
| PathBank:SMP0000168 | AICA-Ribosiduria |
| PathBank:SMP0000172 | beta-Ureidopropionase Deficiency |
| PathBank:SMP0000427 | Azathioprine Action Pathway |
| PathBank:SMP0087239 | Purine Metabolism |