Cell recruitment (pro-inflammatory response)

Cekic C, Linden J. Purinergic regulation of the immune system. Nat Rev Immunol. 2016 Mar;16(3):177–92. doi: 10.1038/nri.2016.4. PMID: 26922909.; Navas A, Vargas DA, Freudzon M, McMahon-Pratt D, Saravia NG, Gómez MA. Chronicity of dermal leishmaniasis caused by Leishmania panamensis is associated with parasite-mediated induction of chemokine gene expression. Infect Immun. 2014 Jul;82(7):2872–80. PMID: 24752514; PMCID: PMC4097649.; Lai Y, Gallo RL. Toll-like receptors in skin infections and inflammatory diseases. Infect Disord Drug Targets. 2008 Sep;8(3):144–55. PMID: 18782031; PMCID: PMC2744356.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Nicotinamide-beta-riboside

Formula: C11H15N2O5 (255.098092)

CAS ID: 1341-23-7

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:



Enzyme

EC Number name full name note
3.6.4.-
1.14.14.18 heme oxygenase (biliverdin-producing) protoheme,NADPH-hemoprotein reductase:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)
3.1.3.35 thymidylate 5'-phosphatase thymidylate 5'-phosphohydrolase
3.1.3.5 5'-nucleotidase 5'-ribonucleotide phosphohydrolase
3.1.3.89 5'-deoxynucleotidase 2'-deoxyribonucleoside 5'-monophosphate phosphohydrolase
3.1.3.91 7-methylguanosine nucleotidase N7-methyl-GMP phosphohydrolase
3.1.3.99 IMP-specific 5'-nucleotidase inosine 5'-phosphate phosphohydrolase
3.4.21.20 cathepsin G
3.4.22.36 caspase-1
3.6.1.5 apyrase nucleoside triphosphate phosphohydrolase (nucleoside monophosphoate-forming)
3.6.1.6 nucleoside diphosphate phosphatase nucleoside-diphosphate phosphohydrolase


Proteins

Protein ID name full name