EC: 2.1.1.28

phenylethanolamine N-methyltransferase (S-adenosyl-L-methionine:phenylethanolamine N-methyltransferase)

enzyme lambda metabolic reaction experiment
uniprot:P11086 [trans-(1S,2S)-2-Amino-1-tetralol]

Phenylethanolamine + S_Adenosyl_L_methionine -> S_Adenosyl_L_homocysteine + N_Methylphenylethanolamine		 (( (Vmax * A) ) / (A + (Km * (1 + (I / Ki))))) buffer: 50 mM phosphate
PH: 8
Temperature: 30

Pathways

pathway id name
BioCyc:META_PWY-6342 noradrenaline and adrenaline degradation
BioCyc:META_PWY66-301 catecholamine biosynthesis
BioCyc:MOUSE_PWY66-301 catecholamine biosynthesis
BioCyc:HUMAN_PWY66-301 catecholamine biosynthesis
BioCyc:HUMAN_PWY-6342 noradrenaline and adrenaline degradation
Reactome:R-HSA-209905 Catecholamine biosynthesis
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-209905 Catecholamine biosynthesis
Reactome:R-RNO-209905 Catecholamine biosynthesis
Reactome:R-SSC-209905 Catecholamine biosynthesis
Reactome:R-HSA-209776 Metabolism of amine-derived hormones
Reactome:R-MMU-209776 Metabolism of amine-derived hormones
Reactome:R-RNO-209776 Metabolism of amine-derived hormones
Reactome:R-SSC-1430728 Metabolism
Reactome:R-SSC-209776 Metabolism of amine-derived hormones
Reactome:R-HSA-71291 Amino acid and derivative metabolism
Reactome:R-MMU-71291 Amino acid and derivative metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-71291 Amino acid and derivative metabolism
Reactome:R-SSC-71291 Amino acid and derivative metabolism
Reactome:R-HSA-1430728 Metabolism
WikiPathways:WP5287 17q12 copy number variation syndrome
WikiPathways:WP4220 Neurotransmitter disorders
WikiPathways:WP4156 Biosynthesis and regeneration of tetrahydrobiopterin and catabolism of phenylalanine
PathBank:SMP0120674 Alkaptonuria
PathBank:SMP0120782 Dopamine beta-Hydroxylase Deficiency
PathBank:SMP0000190 Hawkinsinuria
PathBank:SMP0087330 Tryptophan Metabolism
PathBank:SMP0087334 Nicotinate and Nicotinamide Metabolism
PathBank:SMP0120729 Tyrosinemia Type I
PathBank:SMP0120817 Monoamine Oxidase-A Deficiency (MAO-A)
PathBank:SMP0000169 Alkaptonuria
PathBank:SMP0000429 Disulfiram Action Pathway
PathBank:SMP0087237 Tryptophan Metabolism
PathBank:SMP0087241 Nicotinate and Nicotinamide Metabolism
PathBank:SMP0000218 Tyrosinemia Type I
PathBank:SMP0000497 Tyrosine Hydroxylase Deficiency
PathBank:SMP0000533 Monoamine Oxidase-A Deficiency (MAO-A)
PathBank:SMP0087328 Tyrosine Metabolism
PathBank:SMP0120711 Hawkinsinuria
PathBank:SMP0120779 Tyrosinemia, Transient, of the Newborn
PathBank:SMP0000006 Tyrosine Metabolism
PathBank:SMP0000012 Catecholamine Biosynthesis
PathBank:SMP0000170 Aromatic L-Aminoacid Decarboxylase Deficiency
PathBank:SMP0000494 Tyrosinemia, Transient, of the Newborn
PathBank:SMP0000498 Dopamine beta-Hydroxylase Deficiency
PathBank:SMP0087235 Tyrosine Metabolism