KEGG:R10515
three-step reaction (see R01840+R04759+R02351)
androst-4-ene-3,17-dione monooxygenase (estrone-forming)
Androstenedione[C19H26O2] + 3 Oxygen[O2] + 3 [Reduced NADPH---hemoprotein reductase][] = Estrone[C18H22O2] + Formate[CH2O2] + 4 H2O[H2O] + 3 [Oxidized NADPH---hemoprotein reductase][]
DB Links
- KEGG: R10515
- EC Number: 1.14.14.14
Alias
Metabolites
Substrates
| metabolite | compartment | Structure |
|---|---|---|
| Androstenedione Formula: C19H26O2 |
Cytoplasm | |
| Oxygen Formula: O2 |
Cytoplasm | |
| [Reduced NADPH---hemoprotein reductase] Formula: |
Cytoplasm |
Products
| metabolite | compartment | Structure |
|---|---|---|
| Estrone Formula: C18H22O2 |
Cytoplasm | |
| Formate Formula: CH2O2 |
Cytoplasm | |
| H2O Formula: H2O |
Cytoplasm | |
| [Oxidized NADPH---hemoprotein reductase] Formula: |
Cytoplasm |