cysG

K02302 cysG; uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]

Protein Function: uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]

DBLinks
Proteins
protein id name function taxonomy source
Reactions
reaction id name note
KEGG:R03947 S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase multifunctional enzyme: siroheme synthase: precorrin-2 dehydrogenase (R03194+R03947+R02864)
BioCyc:DIMETHUROPORDEHYDROG-RXN DIHYDROSIROHYDROCHLORIN + NAD --> 2 PROTON + SIROHYDROCHLORIN + NADH
Rhea:RHEA:15614 precorrin-2 + NAD+ => sirohydrochlorin + NADH + 2 H+
Rhea:RHEA:15615 sirohydrochlorin + NADH + 2 H+ => precorrin-2 + NAD+
Rhea:RHEA:15616 precorrin-2 + NAD+ <=> sirohydrochlorin + NADH + 2 H+
KEGG:R03194 S-adenosyl-L-methionine:uroporphyrinogen-III C-methyltransferase multifunctional enzyme: siroheme synthase: uroporphyrinogen III methyltransferase (R03194+R03947+R02864)
KEGG:R03950 S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase incomplete reaction, possibly incorrect (see R03194)
KEGG:R07237 S-adenosyl-L-methionine:uroporphyrinogen-III C-methyltransferase first step of two-step reaction (R03194, R07237+R07238), subsequently R07238
KEGG:R07238 S-adenosyl-L-methionine:precorrin-1 C-methyltransferase second step of two-step reaction (R03194, R07237+R07238), following after R07237
BioCyc:RXN-13403 2 S-ADENOSYLMETHIONINE + UROPORPHYRINOGEN-III --> 2 ADENOSYL-HOMO-CYS + DIHYDROSIROHYDROCHLORIN + PROTON