Pathways Knowlegdes

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Pathway DOIs Note
CMP-N-acetylneuraminate biosynthesis I (eukaryotes)

Accession ID: BioCyc:HUMAN_PWY-6138
  • 10.1007/s10719-006-6484-y
  • 10.1016/j.bioorg.2005.01.005
  • 10.1016/j.jmb.2007.03.037
 Ghaderi D, Strauss HM, Reinke S, Cirak S, Reutter W, Lucka L, Hinderlich S. Evidence for dynamic interplay of different oligomeric states of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase by biophysical methods. J Mol Biol. 2007 Jun 08;369(3):746–58. doi: 10.1016/j.jmb.2007.03.037. PMID: 17448495.; Inoue S, Kitajima K. KDN (deaminated neuraminic acid): dreamful past and exciting future of the newest member of the sialic acid family. Glycoconj J. 2006 Jul;23(5-6):277–90. doi: 10.1007/s10719-006-6484-y. PMID: 16897172.; Tanner ME. The enzymes of sialic acid biosynthesis. Bioorg Chem. 2005 Jun;33(3):216–28. doi: 10.1016/j.bioorg.2005.01.005. PMID: 15888312.
5-aminoimidazole ribonucleotide biosynthesis

Accession ID: BioCyc:HUMAN_PWY-6121
  • 10.1039/c3cc41437j
 Zhao H, French JB, Fang Y, Benkovic SJ. The purinosome, a multi-protein complex involved in the de novo biosynthesis of purines in humans. Chem Commun (Camb). 2013 May 18;49(40):4444–52. PMID: 23575936; PMCID: PMC3877848.
NADH repair

Accession ID: BioCyc:HUMAN_PWY-6938
  • 10.1074/jbc.c111.310847
 Marbaix AY, Noël G, Detroux AM, Vertommen D, Van Schaftingen E, Linster CL. Extremely Conserved ATP- or ADP-dependent Enzymatic System for Nicotinamide Nucleotide Repair. Journal of Biological Chemistry. 2011 Dec;286(48):41246–52. doi: 10.1074/jbc.c111.310847.
NAD phosphorylation and dephosphorylation

Accession ID: BioCyc:HUMAN_NADPHOS-DEPHOS-PWY-1		 -
urea cycle

Accession ID: BioCyc:HUMAN_PWY-4984
  • 10.1146/annurev.ge.20.120186.002243
 Jackson MJ, Beaudet AL, O'Brien WE. Mammalian urea cycle enzymes. Annu Rev Genet. 1986;20():431–64. doi: 10.1146/annurev.ge.20.120186.002243. PMID: 3545062.
sphingosine and sphingosine-1-phosphate metabolism

Accession ID: BioCyc:HUMAN_PWY3DJ-11470
  • 10.1002/jcb.20097
 Le Stunff H, Milstien S, Spiegel S. Generation and metabolism of bioactive sphingosine-1-phosphate. J Cell Biochem. 2004 Aug 01;92(5):882–99. doi: 10.1002/jcb.20097. PMID: 15258913.
glycerol degradation

Accession ID: BioCyc:HUMAN_PWY-4261		 -
biotin-carboxyl carrier protein assembly

Accession ID: BioCyc:HUMAN_PWY0-1264		 -
inosine-5'-phosphate biosynthesis

Accession ID: BioCyc:HUMAN_PWY-6124
  • 10.1039/c3cc41437j
 Zhao H, French JB, Fang Y, Benkovic SJ. The purinosome, a multi-protein complex involved in the de novo biosynthesis of purines in humans. Chem Commun (Camb). 2013 May 18;49(40):4444–52. PMID: 23575936; PMCID: PMC3877848.
GDP-glucose biosynthesis II

Accession ID: BioCyc:HUMAN_PWY-5661-1
  • 10.1016/s0021-9258(18)60318-7
 Carlson DM, Hansen RG. The Isolation and Synthesis of Guanosine Diphosphate Glucose. Journal of Biological Chemistry. 1962 Apr;237(4):1260–5. doi: 10.1016/s0021-9258(18)60318-7.
purine deoxyribonucleosides salvage

Accession ID: BioCyc:HUMAN_PWY-7224		 -
proline biosynthesis

Accession ID: BioCyc:HUMAN_PROSYN-PWY
  • 10.1016/s0021-9258(18)60538-1
 Merrill MJ, Yeh GC, Phang JM. Purified Human Erythrocyte Pyrroline-5-carboxylate Reductase. Journal of Biological Chemistry. 1989 Jun;264(16):9352–8. doi: 10.1016/s0021-9258(18)60538-1.
N-acetylglucosamine degradation II

Accession ID: BioCyc:HUMAN_PWY-6517		 -
folate polyglutamylation

Accession ID: BioCyc:HUMAN_PWY-2161		 -
glycolysis

Accession ID: BioCyc:HUMAN_PWY66-400
  • 10.1101/gad.189365.112
 Dang CV. Links between metabolism and cancer. Genes Dev. 2012 May 01;26(9):877–90. PMID: 22549953; PMCID: PMC3347786.
3-phosphoinositide biosynthesis

Accession ID: BioCyc:HUMAN_PWY-6352
  • 10.1002/bies.950160810
 Kapeller R, Cantley LC. Phosphatidylinositol 3-kinase. Bioessays. 1994 Aug;16(8):565–76. doi: 10.1002/bies.950160810. PMID: 8086005.
pyrimidine ribonucleosides salvage I

Accession ID: BioCyc:HUMAN_PWY-7193		 -
inositol pyrophosphates biosynthesis

Accession ID: BioCyc:HUMAN_PWY-6369
  • 10.1074/jbc.275.17.12730
 Caffrey JJ, Safrany ST, Yang X, Shears SB. Discovery of molecular and catalytic diversity among human diphosphoinositol-polyphosphate phosphohydrolases. An expanding Nudt family. J Biol Chem. 2000 Apr 28;275(17):12730–6. doi: 10.1074/jbc.275.17.12730. PMID: 10777568.
D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis

Accession ID: BioCyc:HUMAN_PWY-6366
  • 10.1016/j.bbrc.2005.10.201
 Chang S, Majerus PW. Inositol polyphosphate multikinase regulates inositol 1,4,5,6-tetrakisphosphate. Biochemical and Biophysical Research Communications. 2006 Jan;339(1):209–16. doi: 10.1016/j.bbrc.2005.10.201.
superpathway of methionine degradation

Accession ID: BioCyc:HUMAN_PWY-5328		 -