Pathways Knowlegdes
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| Pathway | DOIs | Note |
|---|---|---|
| Deregulation of renin-angiotensin system by SARS-CoV infection Accession ID: WikiPathways:WP4965 |
|
Kuba K, Imai Y, Rao S, Gao H, Guo F, Guan B, Huan Y, Yang P, Zhang Y, Deng W, Bao L, Zhang B, Liu G, Wang Z, Chappell M, Liu Y, Zheng D, Leibbrandt A, Wada T, Slutsky AS, Liu D, Qin C, Jiang C, Penninger JM. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat Med. 2005 Aug;11(8):875–9. PMID: 16007097; PMCID: PMC7095783. |
| SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction Accession ID: WikiPathways:WP5183 |
|
Gatti P, Ilamathi HS, Todkar K, Germain M. Mitochondria Targeted Viral Replication and Survival Strategies-Prospective on SARS-CoV-2. Front Pharmacol. 2020;11():578599. PMID: 32982760; PMCID: PMC7485471. |
| SARS-CoV-2 and ACE2 receptor: molecular mechanisms Accession ID: WikiPathways:WP4883 |
|
Zhang H, Penninger JM, Li Y, Zhong N, Slutsky AS. Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target. Intensive Care Medicine. 2020 Mar 03;46(4):586–90. doi: 10.1007/s00134-020-05985-9. |
| Mitochondrial immune response to SARS-CoV-2 Accession ID: WikiPathways:WP5038 |
|
Suhail S, Zajac J, Fossum C, Lowater H, McCracken C, Severson N, Laatsch B, Narkiewicz-Jodko A, Johnson B, Liebau J, Bhattacharyya S, Hati S. Role of Oxidative Stress on SARS-CoV (SARS) and SARS-CoV-2 (COVID-19) Infection: A Review. The Protein Journal. 2020 Oct 26;39(6):644–56. doi: 10.1007/s10930-020-09935-8. |
| Angiotensin II receptor type 1 pathway Accession ID: WikiPathways:WP5036 |
|
Ford CM, Li S, Pickering JG. Angiotensin II stimulates collagen synthesis in human vascular smooth muscle cells. Involvement of the AT(1) receptor, transforming growth factor-beta, and tyrosine phosphorylation. Arterioscler Thromb Vasc Biol. 1999 Aug;19(8):1843–51. doi: 10.1161/01.atv.19.8.1843. PMID: 10446062. |
| Renin-angiotensin system Accession ID: WikiPathways:WP376 |
|
Rafiq K, Kolpakov MA, Abdelfettah M, Streblow DN, Hassid A, Dell'Italia LJ, Sabri A. Role of Protein-tyrosine Phosphatase SHP2 in Focal Adhesion Kinase Down-regulation during Neutrophil Cathepsin G-induced Cardiomyocytes Anoikis. Journal of Biological Chemistry. 2006 Jul;281(28):19781–92. doi: 10.1074/jbc.m513040200. |