SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction

Gatti P, Ilamathi HS, Todkar K, Germain M. Mitochondria Targeted Viral Replication and Survival Strategies-Prospective on SARS-CoV-2. Front Pharmacol. 2020;11():578599. PMID: 32982760; PMCID: PMC7485471.

Metabolites

(13E)-(15S)-15-Hydroxy-9-oxoprosta-11,13-dienoate

Formula: C20H32O4 (336.2300472)

CAS ID: 35687-86-6

Angiotensin (1-7)

Formula: C41H62N12O11 (898.4660782)

CAS ID: 51833-78-4

Angiotensin (1-9)

Formula: C56H78N16O13 (1182.5933977999998)

CAS ID: 34273-12-6

Angiotensin I

Formula: C62H89N17O14 (1295.6774574)

CAS ID: 9041-90-1

Angiotensin II

Formula: C50H71N13O12 (1045.5344885999998)

CAS ID: 11128-99-7



Enzyme

EC Number name full name note
3.1.13.-
2.1.1.56 mRNA (guanine-N7)-methyltransferase S-adenosyl-L-methionine:mRNA (guanine-N7)-methyltransferase
2.1.1.57 methyltransferase cap1 S-adenosyl-L-methionine:5-(N7-methyl 5-triphosphoguanosine)-(ribonucleotide)-[mRNA] 2-O-methyltransferase
2.7.7.48 RNA-directed RNA polymerase nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)
2.7.7.50 mRNA guanylyltransferase GTP:mRNA guanylyltransferase
3.4.19.12 ubiquitinyl hydrolase 1
3.4.22.69 SARS coronavirus main proteinase
3.6.4.12 DNA helicase
3.6.4.13 RNA helicase


Proteins

Protein ID name full name