Pathways Knowlegdes

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Pathway DOIs Note
tryptophan degradation via kynurenine

Accession ID: BioCyc:CALBI_TRYPTOPHAN-DEGRADATION-1
  • 10.1002/jobm.19740140508
  • 10.1016/s0014-5793(02)02585-1
  • 10.1271/bbb.69.2358
TSAI S, TSAI L, LI Y. An IsolatedCandida albicansTL3 Capable of Degrading Phenol at Large Concentration. Bioscience, Biotechnology, and Biochemistry. 2005 Jan;69(12):2358–67. doi: 10.1271/bbb.69.2358.; Panozzo C, Nawara M, Suski C, Kucharczyk R, Skoneczny M, Bécam A, Rytka J, Herbert CJ. Aerobic and anaerobic NAD+ metabolism in Saccharomyces cerevisiae. FEBS Letters. 2002 Mar 22;517(1-3):97–102. doi: 10.1016/s0014-5793(02)02585-1.; Teuscher G, Karczewski P, Weide H. [Catabolism of tryptophan by Candida guilliermondii, strain H17]. Z Allg Mikrobiol. 1974;14(5):429–33. doi: 10.1002/jobm.3630140508. PMID: 4408763.
NAD biosynthesis (from tryptophan)

Accession ID: BioCyc:CALBI_NADSYN-PWY
  • 10.1016/j.tibs.2006.11.006
  • 10.1111/j.1567-1364.2007.00231.x
  • 10.1128/jb.139.3.883-888.1979
Li YF, Bao WG. Why do some yeast species require niacin for growth? Different modes of NAD synthesis. FEMS Yeast Res. 2007 Aug;7(5):657–64. doi: 10.1111/j.1567-1364.2007.00231.x. PMID: 17425674.; Belenky P, Bogan KL, Brenner C. NAD+ metabolism in health and disease. Trends Biochem Sci. 2007 Jan;32(1):12–9. doi: 10.1016/j.tibs.2006.11.006. PMID: 17161604.; Chaffin WL, Barton RA, Jacobson EL, Jacobson MK. Nicotinamide adenine dinucleotide metabolism in Candida albicans. J Bacteriol. 1979 Sep;139(3):883–8. doi: 10.1128/jb.139.3.883-888.1979.
NAD biosynthesis II from tryptophan

Accession ID: WikiPathways:WP3228
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Biochemical pathways: part I

Accession ID: WikiPathways:WP3604
  • 10.1016/s0303-2647(98)00019-7
Michal G. On representation of metabolic pathways. Biosystems. 1998 Jun;47(1-2):1–7. doi: 10.1016/s0303-2647(98)00019-7. PMID: 9715748.
Kynurenine pathway and links to cell senescence

Accession ID: WikiPathways:WP5044
  • 10.1038/s41380-019-0414-4
Savitz J. The kynurenine pathway: a finger in every pie. Molecular Psychiatry. 2019 Apr 12;25(1):131–47. doi: 10.1038/s41380-019-0414-4.
NAD biosynthesis II (from tryptophan)

Accession ID: WikiPathways:WP2485
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NAD+ biosynthetic pathways

Accession ID: WikiPathways:WP3645
  • 10.1126/science.aac4854
Verdin E. NAD? in aging, metabolism, and neurodegeneration. Science. 2015 Dec 04;350(6265):1208–13. doi: 10.1126/science.aac4854. PMID: 26785480.
Tryptophan Metabolism

Accession ID: PathBank:SMP0002353
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Tryptophan Metabolism

Accession ID: PathBank:SMP0087330
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Tryptophan Metabolism

Accession ID: PathBank:SMP0087237
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Tryptophan Metabolism

Accession ID: PathBank:SMP0063693
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Tryptophan Metabolism

Accession ID: PathBank:SMP0000063
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NAD Metabolism

Accession ID: PathBank:SMP0002338
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Tryptophan Metabolism

Accession ID: PathBank:SMP0087451
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