methylerythritol phosphate pathway II

Vranová E, Coman D, Gruissem W. Network analysis of the MVA and MEP pathways for isoprenoid synthesis. Annu Rev Plant Biol. 2013;64():665–700. doi: 10.1146/annurev-arplant-050312-120116. PMID: 23451776.

Metabolites

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

Cobalt ion

Formula: Co (58.933198)

CAS ID: 22541-53-3

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Manganese(2+)

Formula: Mn (54.938046)

CAS ID: 7439-96-5

Nickel(2+)

Formula: Ni (57.935347)

CAS ID: 14701-22-5

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
1.1.1.267 1-deoxy-D-xylulose-5-phosphate reductoisomerase 2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing)
1.17.7.4 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase isopentenyl-diphosphate:ferredoxin oxidoreductase
2.2.1.7 1-deoxy-D-xylulose-5-phosphate synthase pyruvate:D-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating)
2.7.1.148 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase ATP:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol 2-phosphotransferase
2.7.7.60 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
4.6.1.12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate-forming)
5.3.3.2 isopentenyl-diphosphate DELTA-isomerase 3-methylbut-3-en-1-yl-diphosphate DELTA3-DELTA2-isomerase


Proteins

Protein ID name full name