glycolysis III (from glucose)
Dang CV. Links between metabolism and cancer. Genes Dev. 2012 May 01;26(9):877–90. PMID: 22549953; PMCID: PMC3347786.; Hansen T, Schönheit P. ATP-dependent glucokinase from the hyperthermophilic bacterium Thermotoga maritima represents an extremely thermophilic ROK glucokinase with high substrate specificity. FEMS Microbiol Lett. 2003 Sep 26;226(2):405–11. doi: 10.1016/s0378-1097(03)00642-6. PMID: 14553940.; Selig M, Xavier KB, Santos H, Schönheit P. Comparative analysis of Embden-Meyerhof and Entner-Doudoroff glycolytic pathways in hyperthermophilic archaea and the bacterium Thermotoga. Arch Microbiol. 1997 Apr;167(4):217–32. doi: 10.1007/bf03356097. PMID: 9075622.
Metabolites
beta-D-fructofuranose 1,6-bisphosphate(4-)
Formula: C6H10O12P2 (335.96475200000003)
CAS ID: 488-69-7
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.6.99.- | |||
| 1.2.1.12 | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating) | |
| 2.7.1.1 | hexokinase | ATP:D-hexose 6-phosphotransferase | |
| 2.7.1.11 | 6-phosphofructokinase | ATP:D-fructose-6-phosphate 1-phosphotransferase | |
| 2.7.1.2 | glucokinase | ATP:D-glucose 6-phosphotransferase | |
| 2.7.1.40 | pyruvate kinase | ATP:pyruvate 2-O-phosphotransferase | |
| 2.7.10.2 | non-specific protein-tyrosine kinase | ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific) | |
| 2.7.11.1 | non-specific serine/threonine protein kinase | ATP:protein phosphotransferase (non-specific) | |
| 2.7.2.3 | phosphoglycerate kinase | ATP:3-phospho-D-glycerate 1-phosphotransferase | |
| 4.1.2.13 | fructose-bisphosphate aldolase | D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming) | |
| 4.2.1.11 | phosphopyruvate hydratase | 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming) | |
| 4.2.3.3 | methylglyoxal synthase | glycerone-phosphate phosphate-lyase (methylglyoxal-forming) | |
| 5.3.1.1 | triose-phosphate isomerase | D-glyceraldehyde-3-phosphate aldose-ketose-isomerase | |
| 5.3.1.9 | glucose-6-phosphate isomerase | alpha-D-glucose-6-phosphate aldose-ketose-isomerase (configuration-inverting) | |
| 5.4.2.11 | phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) | D-phosphoglycerate 2,3-phosphomutase (2,3-diphosphoglycerate-dependent) | |
| 5.4.2.12 | phosphoglycerate mutase (2,3-diphosphoglycerate-independent) | D-phosphoglycerate 2,3-phosphomutase (2,3-diphosphoglycerate-independent) | |
| 5.4.2.4 | Bisphosphoglycerate mutase | 3-Phospho-D-glycerate 1,2-phosphomutase |
Proteins
| Protein ID | name | full name |
|---|---|---|
| P00925 | ENO2 | Enolase 2 |
| P00950 | GPM1 | Phosphoglycerate mutase 1 |
| P12709 | PGI1 | Glucose-6-phosphate isomerase |
| P16861 | PFK1 | ATP-dependent 6-phosphofructokinase subunit alpha |
| P16862 | PFK2 | ATP-dependent 6-phosphofructokinase subunit beta |
| P17709 | GLK1 | Glucokinase-1 |
| P17721 | TM_0688 | glyceraldehyde-3-phosphate dehydrogenase |
| P36204 | TM_0689 | phosphoglycerate kinase/triose-phosphate isomerase |
| Q9WY51 | TM_0208 | pyruvate kinase |
| Q9WY52 | TM_0209 | 6-phosphofructokinase |
| Q9X1A5 | TM_1385 | glucose-6-phosphate isomerase |
| Q9X1I0 | TM_1469 | glucokinase |
| Q9X295 | TM_1774 | phosphonopyruvate decarboxylase, putative |