superpathway of glycerol degradation to 1,3-propanediol

Rush D, Karibian D, Karnovsky ML, Magasanik B. PATHWAYS OF GLYCEROL DISSIMILATION IN TWO STRAINS OF AEROBACTER AEROGENES: ENZYMATIC AND TRACER STUDIES. Journal of Biological Chemistry. 1957 Jun;226(2):891–9. doi: 10.1016/s0021-9258(18)70875-2.

Metabolites

3-Hydroxypropanal

Formula: C3H6O2 (74.0367776)

CAS ID: 2134-29-4

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

Dithioerythritol

Formula: C4H10O2S2 (154.01222)

CAS ID: 6892-68-8

Fe2+

Formula: Fe (55.934939)

CAS ID: 15438-31-0

Glycerol

Formula: C3H8O3 (92.0473418)

CAS ID: 56-81-5

Glycerone

Formula: C3H6O3 (90.0316926)

CAS ID: 96-26-4

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Manganese(2+)

Formula: Mn (54.938046)

CAS ID: 7439-96-5

Mercaptoethanol

Formula: C2H6OS (78.0139346)

CAS ID: 60-24-2

Mercury(2+)

Formula: Hg (201.970632)

CAS ID: 14302-87-5

N-Ethylmaleimide

Formula: C6H7NO2 (125.0476762)

CAS ID: 128-53-0

Propane-1,3-diol

Formula: C3H8O2 (76.0524268)

CAS ID: 504-63-2

Silver

Formula: Ag (106.905095)

CAS ID: 7440-22-4

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

iodoacetamide

Formula: C2H4INO (184.9337644)

CAS ID: 144-48-9

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
1.1.1.6 glycerol dehydrogenase glycerol:NAD+ 2-oxidoreductase
2.7.1.29 glycerone kinase ATP:glycerone phosphotransferase
4.2.1.30 glycerol dehydratase glycerol hydro-lyase (3-hydroxypropanal-forming)


Proteins

Protein ID name full name
P45510 dhaK Dihydroxyacetone kinase
P45511 dhaD Glycerol dehydrogenase
P45514 dhaB Glycerol dehydratase large subunit