Corticosterone Methyl Oxidase I Deficiency (CMO I)

Metabolites

11-Dehydrocorticosterone

Formula: C21H28O4 (344.19874880000003)

CAS ID: 72-23-1

11-Deoxycorticosterone

Formula: C21H30O3 (330.21948299999997)

CAS ID: 64-85-7

11-Deoxycortisol

Formula: C21H30O4 (346.214398)

CAS ID: 152-58-9

11beta,17alpha,21-Trihydroxypregnenolone

Formula: C21H32O5 (364.2249622)

CAS ID: 1050-84-6

11beta,21-Dihydroxy-5beta-pregnane-3,20-dione

Formula: C21H32O4 (348.2300472)

CAS ID: 566-01-8

17alpha-Hydroxypregnenolone

Formula: C21H32O3 (332.23513219999995)

CAS ID: 387-79-1

17alpha-Hydroxyprogesterone

Formula: C21H30O3 (330.21948299999997)

CAS ID: 68-96-2

17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione

Formula: C21H30O5 (362.209313)

CAS ID: 68-54-2

17alpha,21-Dihydroxypregnenolone

Formula: C21H32O4 (348.2300472)

CAS ID: 1167-48-2

18-Hydroxycorticosterone

Formula: C21H30O5 (362.209313)

CAS ID: 561-65-9

20alpha-Hydroxycholesterol

Formula: C27H46O2 (402.34976159999997)

CAS ID: 516-72-3

20alpha,22beta-Dihydroxycholesterol

Formula: C27H46O3 (418.34467659999996)

CAS ID: 15234-55-6

21-Deoxycortisol

Formula: C21H30O4 (346.214398)

CAS ID: 641-77-0

21-Hydroxy-5beta-pregnane-3,11,20-trione

Formula: C21H30O4 (346.214398)

CAS ID: 10417-86-4

21-Hydroxypregnenolone

Formula: C21H32O3 (332.23513219999995)

CAS ID: 1164-98-3

22(R)-Hydroxycholesterol

Formula: C27H46O2 (402.34976159999997)

CAS ID: 17954-98-2

3alpha,11beta,21-Trihydroxy-20-oxo-5beta-pregnan-18-al

Formula: C21H32O5 (364.2249622)

CAS ID:

3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione

Formula: C21H32O4 (348.2300472)

CAS ID: 566-03-0

4-Methylpentanal

Formula: C6H12O (100.0888102)

CAS ID: 1119-16-0

5alpha-Pregnane-3,20-dione

Formula: C21H32O2 (316.24021719999996)

CAS ID: 566-65-4

Cholesterol

Formula: C27H46O (386.3548466)

CAS ID: 57-88-5

Corticosterone

Formula: C21H30O4 (346.214398)

CAS ID: 50-22-6

Cortisol

Formula: C21H30O5 (362.209313)

CAS ID: 50-23-7

Cortisone

Formula: C21H28O5 (360.1936638)

CAS ID: 53-06-5

Dihydrocortisol

Formula: C21H32O5 (364.2249622)

CAS ID: 1482-50-4

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

NAD+

Formula: C21H28N7O14P2 (664.1169428000001)

CAS ID: 53-84-9

NADH

Formula: C21H29N7O14P2 (665.1247674)

CAS ID: 58-68-4

NADP+

Formula: C21H29N7O17P3 (744.0832754)

CAS ID: 53-59-8

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Pregnanolone

Formula: C21H34O2 (318.2558664)

CAS ID: 128-20-1

Progesterone

Formula: C21H30O2 (314.224568)

CAS ID: 57-83-0

Tetrahydrocortisone

Formula: C21H32O5 (364.2249622)

CAS ID: 53-05-4

11b-Hydroxyprogesterone

Formula: C20H28O4 (332.19874880000003)

CAS ID:



Enzyme

EC Number name full name note
1.1.1.-
1.14.14.16 steroid 21-monooxygenase steroid,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating)
1.14.15.4 steroid 11beta-monooxygenase steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11beta-hydroxylating)
1.3.1.3 DELTA4-3-oxosteroid 5beta-reductase 5beta-cholestan-3-one:NADP+ 4,5-oxidoreductase


Proteins

Protein ID name full name