superpathway of purine nucleotides de novo biosynthesis I
Metabolites
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(2-)
Formula: C9H13N4O8P (336.0470988)
CAS ID:
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 1.-.-.- | |||
| 1.1.1.205 | IMP dehydrogenase | IMP:NAD+ oxidoreductase | |
| 1.17.4.1 | ribonucleoside-diphosphate reductase | 2'-deoxyribonucleoside-5'-diphosphate:thioredoxin-disulfide 2'-oxidoreductase | |
| 1.7.1.7 | GMP reductase | inosine-5'-phosphate:NADP+ oxidoreductase (aminating) | |
| 2.1.2.2 | phosphoribosylglycinamide formyltransferase 1 | 10-formyltetrahydrofolate:5'-phosphoribosylglycinamide N-formyltransferase | |
| 2.1.2.3 | phosphoribosylaminoimidazolecarboxamide formyltransferase | 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazole-carboxamide N-formyltransferase | |
| 2.4.2.14 | amidophosphoribosyltransferase | 5-phospho-beta-D-ribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating) | |
| 2.7.4.3 | adenylate kinase | ATP:AMP phosphotransferase | |
| 2.7.4.6 | nucleoside-diphosphate kinase | ATP:nucleoside-diphosphate phosphotransferase | |
| 3.5.1.2 | glutaminase | L-glutamine amidohydrolase | |
| 3.5.4.10 | IMP cyclohydrolase | IMP 1,2-hydrolase (decyclizing) | |
| 4.3.3.6 | pyridoxal 5'-phosphate synthase (glutamine hydrolysing) | D-ribose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5'-phosphate-lyase | |
| 5.4.99.18 | 5-(carboxyamino)imidazole ribonucleotide mutase | 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole carboxymutase | |
| 6.3.2.6 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming) | |
| 6.3.4.13 | phosphoribosylamine-glycine ligase | 5-phospho-D-ribosylamine:glycine ligase (ADP-forming) | |
| 6.3.4.18 | 5-(carboxyamino)imidazole ribonucleotide synthase | 5-amino-1-(5-phospho-D-ribosyl)imidazole:carbon-dioxide ligase (ADP-forming) | |
| 6.3.4.4 | adenylosuccinate synthase | IMP:L-aspartate ligase (GDP-forming) | |
| 6.3.5.2 | GMP synthase (glutamine-hydrolysing) | xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming) | |
| 6.3.5.3 | phosphoribosylformylglycinamidine synthase | N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming) | |
| 7.1.2.2 | H+-transporting two-sector ATPase | ATP phosphohydrolase (H+-transporting) |
Proteins
| Protein ID | name | full name |
|---|---|---|
| P9WH68 | nrdB | R2-like ligand binding oxidase |
| P9WH70 | nrdF2 | Ribonucleoside-diphosphate reductase subunit beta nrdF2 |
| P9WH72 | nrdF1 | Ribonucleoside-diphosphate reductase subunit beta nrdF1 |
| P9WH74 | nrdE | Ribonucleoside-diphosphate reductase subunit alpha |
| P9WHL4 | purQ | Phosphoribosylformylglycinamidine synthase subunit PurQ |
| P9WHL6 | purL | Phosphoribosylformylglycinamidine synthase subunit PurL |
| P9WHL8 | purK | N5-carboxyaminoimidazole ribonucleotide synthase |
| P9WHM0 | purE | N5-carboxyaminoimidazole ribonucleotide mutase |
| P9WHM4 | purN | Phosphoribosylglycinamide formyltransferase |
| P9WHM6 | purH | Bifunctional purine biosynthesis protein PurH |
| P9WHM8 | purD | Phosphoribosylamine--glycine ligase |
| P9WHN0 | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase |
| P9WHN2 | purA | Adenylosuccinate synthetase |
| P9WHQ6 | purF | Amidophosphoribosyltransferase |
| P9WII6 | pdxT | Pyridoxal 5'-phosphate synthase subunit PdxT |
| P9WJH6 | ndkA | Nucleoside diphosphate kinase |
| P9WKF4 | adk | Adenylate kinase |
| P9WKI2 | guaB1 | GMP reductase |
| P9WKI4 | guaB3 | Uncharacterized oxidoreductase MT3518 |
| P9WKI6 | guaB | Inosine-5'-monophosphate dehydrogenase |
| P9WMS6 | guaA | GMP synthase [glutamine-hydrolyzing] |
| P9WPU4 | atpD | ATP synthase subunit beta |
| P9WPU6 | atpA | ATP synthase subunit alpha |