Cholesterol metabolism

Gadbut AP, Wu L, Tang D, Papageorge A, Watson JA, Galper JB. Induction of the cholesterol metabolic pathway regulates the farnesylation of RAS in embryonic chick heart cells: a new role for ras in regulating the expression of muscarinic receptors and G proteins. EMBO J. 1997 Dec 15;16(24):7250–60. PMID: 9405354; PMCID: PMC1170325.

Metabolites

(R)-Mevalonate

Formula: C6H12O4 (148.0735552)

CAS ID: 17817-88-8

(S)-2,3-Epoxysqualene

Formula: C30H50O (426.386145)

CAS ID: 54910-48-4

(S)-3-Hydroxy-3-methylglutaryl-CoA

Formula: C27H44N7O20P3S (911.1574614)

CAS ID: 1553-55-5

7-Dehydrocholesterol

Formula: C27H44O (384.3391974)

CAS ID: 434-16-2

Acetoacetyl-CoA

Formula: C25H40N7O18P3S (851.136333)

CAS ID: 1420-36-6

Acetyl-CoA

Formula: C23H38N7O17P3S (809.1257688000001)

CAS ID: 72-89-9

Cholesterol

Formula: C27H46O (386.3548466)

CAS ID: 57-88-5

Dimethylallyl diphosphate

Formula: C5H12O7P2 (246.0058262)

CAS ID: 358-72-5

Geranyl diphosphate

Formula: C10H20O7P2 (314.068423)

CAS ID: 763-10-0

Isopentenyl diphosphate

Formula: C5H12O7P2 (246.0058262)

CAS ID: 358-71-4

Lanosterol

Formula: C30H50O (426.386145)

CAS ID: 79-63-0

Lathosterol

Formula: C27H46O (386.3548466)

CAS ID: 80-99-9

Squalene

Formula: C30H50 (410.39123)

CAS ID: 111-02-4

trans,trans-Farnesyl diphosphate

Formula: C15H28O7P2 (382.1310198)

CAS ID: 372-97-4

(R)-Mevalonic acid-5-pyrophosphate

Formula: C6H14O10P2 (308.0062204)

CAS ID: 1492-08-6



Enzyme

EC Number name full name note


Proteins

Protein ID name full name