Insulin receptor signalling cascade

Bevan P. Insulin signalling. J Cell Sci. 2001 Apr;114(Pt 8):1429–30. doi: 10.1242/jcs.114.8.1429. PMID: 11282018.; Shepherd PR, Withers DJ, Siddle K. Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling. Biochem J. 1998 Aug 01;333 ( Pt 3)():471–90. PMID: 9677303; PMCID: PMC1219607.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

adenosine 5'-monophosphate(2-)

Formula: C10H12N5O7P (345.0474332)

CAS ID:

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

3',5'-cyclic AMP(1-)

Formula: C10H11N5O6P (328.0446936)

CAS ID: 62906-31-4



Enzyme

EC Number name full name note
2.7.10.1 receptor protein-tyrosine kinase ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type)
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase 3',5'-cyclic-nucleotide 5'-nucleotidohydrolase


Proteins

Protein ID name full name