Amine Oxidase reactions

Benedetti MS. Biotransformation of xenobiotics by amine oxidases. Fundam Clin Pharmacol. 2001 Apr;15(2):75–84. doi: 10.1046/j.1472-8206.2001.00011.x. PMID: 11468017.; Beedham C. The role of non—P450 enzymes in drug oxidation. International Journal of Clinical Pharmacy. 1997 Dec;19(6):255–63. doi: 10.1023/a:1008668913093.; Tabor CW, Tabor H. Polyamines. Annu Rev Biochem. 1984;53():749–90. doi: 10.1146/annurev.bi.53.070184.003533. PMID: 6206782.

Metabolites

3-Acetamidopropanal

Formula: C5H9NO2 (115.0633254)

CAS ID: 73323-68-9

4-Hydroxyphenylacetaldehyde

Formula: C8H8O2 (136.0524268)

CAS ID: 7339-87-9

5-Hydroxyindoleacetaldehyde

Formula: C10H9NO2 (175.0633254)

CAS ID: 1892-21-3

Ammonia

Formula: NH3 (17.0265478)

CAS ID: 7664-41-7

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydrogen peroxide

Formula: H2O2 (34.0054792)

CAS ID: 7722-84-1

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Phenethylamine

Formula: C8H11N (121.0891446)

CAS ID: 64-04-0

Phenylacetaldehyde

Formula: C8H8O (120.0575118)

CAS ID: 122-78-1

Tyramine

Formula: C8H11NO (137.0840596)

CAS ID: 51-67-2

3-amino-propanal

Formula: C3H8NO (74.0605858)

CAS ID:

N(1)-acetylsperminium(3+)

Formula: C12H31N4O (247.24977359999997)

CAS ID:

serotonin(1+)

Formula: C10H13N2O (177.1027828)

CAS ID:



Enzyme

EC Number name full name note
1.4.3.21 primary-amine oxidase primary-amine:oxygen oxidoreductase (deaminating)
1.4.3.4 monoamine oxidase amine:oxygen oxidoreductase (deaminating)
1.5.3.13 N1-acetylpolyamine oxidase N1-acetylpolyamine:oxygen oxidoreductase (3-acetamidopropanal-forming)
1.5.3.16 spermine oxidase spermidine:oxygen oxidoreductase (spermidine-forming)


Proteins

Protein ID name full name