Base Excision Repair
Sokhansanj BA, Rodrigue GR, Fitch JP, Wilson DM. A quantitative model of human DNA base excision repair. I. Mechanistic insights. Nucleic Acids Res. 2002 Apr 15;30(8):1817–25. PMID: 11937636; PMCID: PMC113225.; Lindahl T, Wood RD. Quality control by DNA repair. Science. 1999 Dec 03;286(5446):1897–905. doi: 10.1126/science.286.5446.1897. PMID: 10583946.
Metabolites
2,6-diamino-5-formamido-4-hydroxypyrimidine
Formula: C5H7N5O2 (169.05997220000003)
CAS ID: 133310-38-0
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 3.1.-.- | |||
| 2.7.1.78 | polynucleotide 5'-hydroxyl-kinase | ATP:5'-dephosphopolynucleotide 5'-phosphotransferase | |
| 2.7.7.7 | DNA-directed DNA polymerase | deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) | |
| 3.1.11.2 | exodeoxyribonuclease III | ||
| 3.1.3.32 | polynucleotide 3'-phosphatase | polynucleotide 3'-phosphohydrolase | |
| 3.2.1.143 | poly(ADP-ribose) glycohydrolase | ||
| 3.2.2.21 | DNA-3-methyladenine glycosylase II | alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine) | |
| 3.2.2.27 | uracil-DNA glycosylase | uracil-DNA deoxyribohydrolase (uracil-releasing) | |
| 3.2.2.29 | thymine-DNA glycosylase | thymine-DNA deoxyribohydrolase (thymine-releasing) | |
| 3.2.2.31 | adenine glycosylase | adenine-DNA deoxyribohydrolase (adenine-releasing) | |
| 4.2.99.18 | DNA-(apurinic or apyrimidinic site) lyase | DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase | |
| 6.5.1.1 | DNA ligase (ATP) | poly(deoxyribonucleotide)-3'-hydroxyl:5'-phospho-poly(deoxyribonucleotide) ligase (ATP) |
Proteins
| Protein ID | name | full name |
|---|