TP53 Regulates Transcription of Caspase Activators and Caspases
Brough D, Rothwell NJ. Caspase-1-dependent processing of pro-interleukin-1beta is cytosolic and precedes cell death. J Cell Sci. 2007 Mar 01;120(Pt 5):772–81. doi: 10.1242/jcs.03377. PMID: 17284521.; Sadasivam S, Gupta S, Radha V, Batta K, Kundu TK, Swarup G. Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis. Oncogene. 2005 Jan 20;24(4):627–36. doi: 10.1038/sj.onc.1208201. PMID: 15580302.; Rikhof B, Corn PG, El-Deiry WS. Caspase 10 Levels are Increased Following DNA Damage in a p53-Dependent Manner. cbt. 2003 Nov 01;2(6):705–10. doi: 10.4161/cbt.2.6.626.; MacLachlan TK, El-Deiry WS. Apoptotic threshold is lowered by p53 transactivation of caspase-6. Proc Natl Acad Sci U S A. 2002 Jul 09;99(14):9492–7. PMID: 12089322; PMCID: PMC123168.; Robles AI, Bemmels NA, Foraker AB, Harris CC. APAF-1 is a transcriptional target of p53 in DNA damage-induced apoptosis. Cancer Res. 2001 Sep 15;61(18):6660–4. PMID: 11559530.; Gupta S, Radha V, Furukawa Y, Swarup G. Direct Transcriptional Activation of Human Caspase-1 by Tumor Suppressor p53. Journal of Biological Chemistry. 2001 Apr;276(14):10585–8. doi: 10.1074/jbc.c100025200.; Lin Y, Ma W, Benchimol S. Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis. Nat Genet. 2000 Sep;26(1):122–7. doi: 10.1038/79102. PMID: 10973264.