2-oxoisovalerate decarboxylation to isobutanoyl-CoA

Metabolites

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

3-methyl-2-oxobutanoate

Formula: C5H7O3 (115.0395172)

CAS ID:

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9



Enzyme

EC Number name full name note
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) 3-methyl-2-oxobutanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating)
1.8.1.4 dihydrolipoyl dehydrogenase protein-N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
2.3.1.168 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase 2-methylpropanoyl-CoA:enzyme-N6-(dihydrolipoyl)lysine S-(2-methylpropanoyl)transferase


Proteins

Protein ID name full name
O34324 acoL Dihydrolipoyl dehydrogenase
P21880 pdhD Dihydrolipoyl dehydrogenase
P37940 bfmBAA 2-oxoisovalerate dehydrogenase subunit alpha
P37941 bfmBAB 2-oxoisovalerate dehydrogenase subunit beta
P37942 bfmBB Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
P54533 bfmBC Dihydrolipoyl dehydrogenase