Glutamate binding, activation of AMPA receptors and synaptic plasticity

Kessels HW, Malinow R. Synaptic AMPA receptor plasticity and behavior. Neuron. 2009 Feb 12;61(3):340–50. PMID: 19217372; PMCID: PMC3917551.; Lee H. Synaptic plasticity and phosphorylation. Pharmacology & Therapeutics. 2006 Dec;112(3):810–32. doi: 10.1016/j.pharmthera.2006.06.003.; Cull-Candy S, Kelly L, Farrant M. Regulation of Ca2+-permeable AMPA receptors: synaptic plasticity and beyond. Curr Opin Neurobiol. 2006 Jun;16(3):288–97. doi: 10.1016/j.conb.2006.05.012. PMID: 16713244.

Metabolites

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

Sodium cation

Formula: Na (22.98977)

CAS ID: 17341-25-2

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.7.11.13 protein kinase C ATP:protein phosphotransferase (diacylglycerol-dependent)
2.7.11.17 Ca2+/calmodulin-dependent protein kinase ATP:protein phosphotransferase (Ca2+/calmodulin-dependent)


Proteins

Protein ID name full name