Programmed Cell Death

Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Campanella M, Candi E, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin K, Di Daniele N, Dixit VM, Dynlacht BD, El-Deiry WS, Fimia GM, Flavell RA, Fulda S, Garrido C, Gougeon M, Green DR, Gronemeyer H, Hajnoczky G, Hardwick JM, Hengartner MO, Ichijo H, Joseph B, Jost PJ, Kaufmann T, Kepp O, Klionsky DJ, Knight RA, Kumar S, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lugli E, Madeo F, Malorni W, Marine J, Martin SJ, Martinou J, Medema JP, Meier P, Melino S, Mizushima N, Moll U, Muñoz-Pinedo C, Nuñez G, Oberst A, Panaretakis T, Penninger JM, Peter ME, Piacentini M, Pinton P, Prehn JH, Puthalakath H, Rabinovich GA, Ravichandran KS, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Shi Y, Simon H, Stockwell BR, Szabadkai G, Tait SW, Tang HL, Tavernarakis N, Tsujimoto Y, Vanden Berghe T, Vandenabeele P, Villunger A, Wagner EF, Walczak H, White E, Wood WG, Yuan J, Zakeri Z, Zhivotovsky B, Melino G, Kroemer G. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death & Differentiation. 2014 Sep 19;22(1):58–73. doi: 10.1038/cdd.2014.137.; Degterev A, Yuan J. Expansion and evolution of cell death programmes. Nature Reviews Molecular Cell Biology. 2008 May;9(5):378–90. doi: 10.1038/nrm2393.

Metabolites

Diethyldithiocarbamic acid

Formula: C5H11NS2 (149.0332886)

CAS ID: 147-84-2

Disulfiram

Formula: C10H20N2S4 (296.050928)

CAS ID: 97-77-8

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

UDP(3-)

Formula: C9H11N2O12P2 (400.9787246)

CAS ID: 86527-70-0

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
3.-.-.-
2.3.1.97 glycylpeptide N-tetradecanoyltransferase tetradecanoyl-CoA:N-terminal-glycine-[protein] N-tetradecanoyltransferase
2.3.2.27 RING-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type)
2.3.2.31 RBR-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:acceptor protein ubiquitin transferase (isopeptide bond-forming; RBR-type)
2.4.1.255 protein O-GlcNAc transferase UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase
2.5.1.58 protein farnesyltransferase farnesyl-diphosphate:protein-cysteine farnesyltransferase
2.5.1.59 protein geranylgeranyltransferase type I geranylgeranyl-diphosphate:protein-cysteine geranyltransferase
2.7.10.2 non-specific protein-tyrosine kinase ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific)
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)
2.7.11.13 protein kinase C ATP:protein phosphotransferase (diacylglycerol-dependent)
2.7.11.24 mitogen-activated protein kinase ATP:protein phosphotransferase (MAPKK-activated)
2.7.11.39 ROCK-subfamily protein kinase ATP:cytoskeleton-protein phosphotransferase
3.4.21.79 granzyme B
3.4.22.36 caspase-1
3.4.22.56 caspase-3
3.4.22.59 caspase-6
3.4.22.61 caspase-8
3.6.4.10 non-chaperonin molecular chaperone ATPase ATP phosphohydrolase (polypeptide-polymerizing)
3.6.5.5 dynamin GTPase GTP phosphohydrolase (vesicle-releasing)


Proteins

Protein ID name full name