Signaling by NOTCH

Schweisguth F. Regulation of Notch Signaling Activity. Current Biology. 2004 Feb;14(3):R129–38. doi: 10.1016/j.cub.2004.01.023.; Mumm JS, Kopan R. Notch signaling: from the outside in. Dev Biol. 2000 Dec 15;228(2):151–65. doi: 10.1006/dbio.2000.9960. PMID: 11112321.; Weinmaster G. Notch signal transduction: a real Rip and more. Current Opinion in Genetics & Development. 2000 Aug;10(4):363–9. doi: 10.1016/s0959-437x(00)00097-6.; Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: cell fate control and signal integration in development. Science. 1999 Apr 30;284(5415):770–6. doi: 10.1126/science.284.5415.770. PMID: 10221902.

Metabolites

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.3.1.-
2.3.1.48 histone acetyltransferase acetyl-CoA:[protein]-L-lysine acetyltransferase
2.3.2.26 HECT-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming)
2.7.10.1 receptor protein-tyrosine kinase ATP:[protein]-L-tyrosine O-phosphotransferase (receptor-type)
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)
2.7.11.13 protein kinase C ATP:protein phosphotransferase (diacylglycerol-dependent)
3.4.21.75 Furin
3.4.24.81 ADAM10 endopeptidase


Proteins

Protein ID name full name