Activation of NMDA receptors and postsynaptic events

Paoletti P, Bellone C, Zhou Q. NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease. Nat Rev Neurosci. 2013 Jun;14(6):383–400. doi: 10.1038/nrn3504. PMID: 23686171.; Hardingham GE, Bading H. Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nature Reviews Neuroscience. 2010 Sep 15;11(10):682–96. doi: 10.1038/nrn2911.; Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R. Glutamate Receptor Ion Channels: Structure, Regulation, and Function. Pharmacological Reviews. 2010 Sep;62(3):405–96. doi: 10.1124/pr.109.002451.; Cohen S, Greenberg ME. Communication Between the Synapse and the Nucleus in Neuronal Development, Plasticity, and Disease. Annu. Rev. Cell Dev. Biol. 2008 Nov 01;24(1):183–209. doi: 10.1146/annurev.cellbio.24.110707.175235.

Metabolites

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

Sodium cation

Formula: Na (22.98977)

CAS ID: 17341-25-2

Ifenprodil

Formula: C21H27NO2 (325.2041682)

CAS ID: 23210-56-2

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

3',5'-cyclic AMP(1-)

Formula: C10H11N5O6P (328.0446936)

CAS ID: 62906-31-4



Enzyme

EC Number name full name note


Proteins

Protein ID name full name