L-tryptophan biosynthesis

Metabolites

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Indole

Formula: C8H7N (117.0578462)

CAS ID: 120-72-9

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3

anthranilate

Formula: C7H6NO2 (136.0398516)

CAS ID: 9031-59-8

pyridoxal 5'-phosphate(2-)

Formula: C8H8NO6P (245.0089238)

CAS ID:



Enzyme

EC Number name full name note
2.4.2.18 anthranilate phosphoribosyltransferase N-(5-phospho-D-ribosyl)-anthranilate:diphosphate phospho-alpha-D-ribosyltransferase
4.1.1.48 indole-3-glycerol-phosphate synthase 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase [cyclizing; 1-C-(indol-3-yl)glycerol-3-phosphate-forming]
4.1.3.27 anthranilate synthase chorismate pyruvate-lyase (amino-accepting; anthranilate-forming)
4.2.1.20 tryptophan synthase L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming]
5.3.1.24 phosphoribosylanthranilate isomerase N-(5-phospho-beta-D-ribosyl)anthranilate aldose-ketose-isomerase


Proteins

Protein ID name full name
P00895 trpE Anthranilate synthase component 1
P00904 trpGD Bifunctional protein TrpGD
P00909 trpC Tryptophan biosynthesis protein TrpCF
P0A877 trpA Tryptophan synthase alpha chain
P0A879 trpB Tryptophan synthase beta chain