Pyruvate metabolism
Prochownik EV, Wang H. The Metabolic Fates of Pyruvate in Normal and Neoplastic Cells. Cells. 2021 Mar 30;10(4). PMID: 33808495; PMCID: PMC8066905.; Reed LJ, Hackert ML. Structure-function relationships in dihydrolipoamide acyltransferases. Journal of Biological Chemistry. 1990 Jun;265(16):8971–4. doi: 10.1016/s0021-9258(19)38795-2.; Cori CF. The glucose-lactic acid cycle and gluconeogenesis. Curr Top Cell Regul. 1981;18():377–87. PMID: 7273846.
Metabolites
beta-D-fructofuranose 1,6-bisphosphate(4-)
Formula: C6H10O12P2 (335.96475200000003)
CAS ID: 488-69-7
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 1.2.4.1 | pyruvate dehydrogenase (acetyl-transferring) | pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating) | |
| 1.8.1.4 | dihydrolipoyl dehydrogenase | protein-N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase | |
| 2.3.1.12 | dihydrolipoyllysine-residue acetyltransferase | acetyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-acetyltransferase | |
| 2.6.1.2 | alanine transaminase | L-alanine:2-oxoglutarate aminotransferase | |
| 2.7.1.40 | pyruvate kinase | ATP:pyruvate 2-O-phosphotransferase | |
| 3.1.2.6 | hydroxyacylglutathione hydrolase | S-(2-hydroxyacyl)glutathione hydrolase | |
| 3.7.1.5 | acylpyruvate hydrolase | 3-acylpyruvate acylhydrolase | |
| 4.1.1.112 | oxaloacetate decarboxylase | oxaloacetate carboxy-lyase (pyruvate-forming) | |
| 5.2.1.2 | maleylacetoacetate isomerase | 4-maleylacetoacetate cis-trans-isomerase |
Proteins
| Protein ID | name | full name |
|---|