Regulation of Homotypic Cell-Cell Adhesion

Malinova TS, Huveneers S. Sensing of Cytoskeletal Forces by Asymmetric Adherens Junctions. Trends Cell Biol. 2018 Apr;28(4):328–41. doi: 10.1016/j.tcb.2017.11.002. PMID: 29195724.; Gul IS, Hulpiau P, Saeys Y, van Roy F. Evolution and diversity of cadherins and catenins. Exp Cell Res. 2017 Sep 01;358(1):3–9. doi: 10.1016/j.yexcr.2017.03.001. PMID: 28268172.; Brasch J, Harrison OJ, Honig B, Shapiro L. Thinking outside the cell: how cadherins drive adhesion. Trends in Cell Biology. 2012 Jun;22(6):299–310. doi: 10.1016/j.tcb.2012.03.004.; Meng W, Takeichi M. Adherens Junction: Molecular Architecture and Regulation. Cold Spring Harbor Perspectives in Biology. 2009 Aug 05;1(6):a002899. doi: 10.1101/cshperspect.a002899.; Yap AS, Brieher WM, Gumbiner BM. Molecular and functional analysis of cadherin-based adherens junctions. Annu Rev Cell Dev Biol. 1997;13():119–46. doi: 10.1146/annurev.cellbio.13.1.119. PMID: 9442870.

Metabolites

beta-D-Glucose

Formula: C6H12O6 (180.0633852)

CAS ID: 492-61-5

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.1.1.-
2.1.1.361 [histone H4]-lysine20 N-methyltransferase S-adenosyl-L-methionine:[histone H4]-L-lysine20 N6-methyltransferase
2.4.99.18 dolichyl-diphosphooligosaccharide-protein glycotransferase dolichyl-diphosphooligosaccharide:protein-L-asparagine N-beta-D-oligopolysaccharidotransferase
3.4.21.89 Signal peptidase I
3.5.1.98 histone deacetylase histone amidohydrolase


Proteins

Protein ID name full name