Regulation of pyruvate metabolism

Metabolites

Cl-

Formula: Cl (34.968853)

CAS ID: 16887-00-6

Glutathione

Formula: C10H17N3O6S (307.08380220000004)

CAS ID: 70-18-8

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Nicotinamide

Formula: C6H6N2O (122.0480106)

CAS ID: 98-92-0

Potassium cation

Formula: K (38.963708)

CAS ID: 24203-36-9

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

dichloroacetate

Formula: C2HCl2O2 (126.93536060000001)

CAS ID: 13425-80-4

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

thiamine(1+) diphosphate(3-)

Formula: C12H16N4O7P2S (422.0214926)

CAS ID:

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring) pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)
1.8.1.4 dihydrolipoyl dehydrogenase protein-N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
2.3.1.286 protein acetyllysine N-acetyltransferase [protein]-N6-acetyl-L-lysine:NAD+ N-acetyltransferase (NAD+-hydrolysing; 2''-O-acetyl-ADP-D-ribose-forming)
2.7.11.2 [pyruvate dehydrogenase (acetyl-transferring)] kinase ATP:[pyruvate dehydrogenase (acetyl-transferring)] phosphotransferase
3.1.3.16 protein-serine/threonine phosphatase protein-serine/threonine-phosphate phosphohydrolase
5.2.1.2 maleylacetoacetate isomerase 4-maleylacetoacetate cis-trans-isomerase


Proteins

Protein ID name full name