a retinoate (BioCAD00000762749)
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Metabolite Card
Formula: C20H27O2 (299.2011)
SMILES: CC(/C=C/C1(/C(CCCC(/C)=1)(C)C))=C\C=C\C(/C)=C\C([O-])=O
Synonyms [en]
a retinoic acid; Vitamin A; a retinoate
Last reviewed on 2024-06-28.
Cite this Page
a retinoate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000762749). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Retinoic acids comprise a biologically active form of retinoids (vitamin A and its derivatives). The spatiotemporal gradient of RA is essential for the regulation of cell proliferation and the differentiation and organ development.There are three stereoisomeric forms of retinoic acid: |FRAME: RETINOATE|, |FRAME: CPD-13549|, and |FRAME: CPD-13548|, which show different binding affinities to the retinoic acid receptors.|FRAME: RETINOATE| is known to bind exclusively to the nuclear retinoic acid receptors (RARs), whereas |FRAME: CPD-13549| binds to both RARs and retinoid x-receptors (RXRs). |FRAME: CPD-13548| is naturally generated in the body, yet it has a 100-fold lower affinity to RARs than |FRAME: RETINOATE| or |FRAME: CPD-13549|, and it does not bind to RXRs.
DBLinks
- CAS Registry Number:
- PubChem CID:
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- HMDB:
- LipidMaps:
- KEGG:
- BioCyc: Retinoates
- NCBI MeSH:
- Wikipedia:
Other DBLinks
- BioCyc: Retinoates