Manganese(2+) (BioCAD00000013712)

blood cerebrospinal fluid (csf) saliva urine basal ganglia brain hair liver

Metabolite Card

Formula: Mn (54.938)
SMILES: [Mn++]

Synonyms [en]

Mn(II); Manganese(II); MN2+; Manganese, ion (Mn2+); Manganese(2+); MN(2+)

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Manganese(2+). 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000013712). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Manganese is an essential trace nutrient in all forms of life. Physiologically, it. exists as an ion in the body. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver.

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 16397-91-4
  • CAS Registry Number: 7439-96-5
  • PubChem: 27854
  • ChEBI: ChEBI:29035
  • HMDB: HMDB0001333
  • KEGG: C19610
  • BioCyc: MN+2
  • Wikipedia: Manganese
  • DrugBank: DB06757

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R00011 1.11.1.13 Mn(II):hydrogen-peroxide oxidoreductase
KEGG:R11880 1.16.3.3 manganese(II):oxygen oxidoreductase
KEGG:R11881 1.16.3.3 4 C19610 + C00007 + 4 C00080<=>4 C19611 + 2 C00001
BioCyc:RXN0-5382 G6420-MONOMER + MN+2<=>CPLX0-7701
BioCyc:TRANS-RXN-241 Mn2+:proton symport
BioCyc:RXN0-16 MN+2 --> MN+2
BioCyc:TRANS-RXN0-487 Mn2+ export
BioCyc:RXN0-7451 CPLX0-7672 + MN+2<=>CPLX0-10669
Rhea:RHEA:17366 7.2.2.5 Mn2+(out) + ATP + H2O => Mn2+(in) + ADP + phosphate + H+
Rhea:RHEA:17367 7.2.2.5 Mn2+(in) + ADP + phosphate + H+ => Mn2+(out) + ATP + H2O
Rhea:RHEA:17368 7.2.2.5 Mn2+(out) + ATP + H2O <=> Mn2+(in) + ADP + phosphate + H+
Rhea:RHEA:22777 1.11.1.13 2 Mn2+ + H2O2 + 2 H+ => 2 Mn3+ + 2 H2O
Rhea:RHEA:22778 1.11.1.13 2 Mn3+ + 2 H2O => 2 Mn2+ + H2O2 + 2 H+
Rhea:RHEA:22779 1.11.1.13 2 Mn2+ + H2O2 + 2 H+ <=> 2 Mn3+ + 2 H2O
Rhea:RHEA:28700 Mn2+(in) => Mn2+(out)
Rhea:RHEA:28701 Mn2+(out) => Mn2+(in)
Rhea:RHEA:28702 Mn2+(in) <=> Mn2+(out)
Rhea:RHEA:29008 Mn2+(in) + H+(in) => Mn2+(out) + H+(out)
Rhea:RHEA:29009 Mn2+(out) + H+(out) => Mn2+(in) + H+(in)
Rhea:RHEA:29010 Mn2+(in) + H+(in) <=> Mn2+(out) + H+(out)
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
BioCyc:HUMAN_PWY-7835 super pathway of glycosphingolipids biosynthesis
BioCyc:HUMAN_PWY-4984 urea cycle
BioCyc:HUMAN_PWY-7434 terminal O-glycans residues modification (via type 2 precursor disaccharide)
BioCyc:HUMAN_PWY-6352 3-phosphoinositide biosynthesis
BioCyc:META_PWY-5290 secologanin and strictosidine biosynthesis
BioCyc:META_PWY-7151 polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)
BioCyc:META_PWY-7981 α-dystroglycan glycosylation
BioCyc:META_PWY-1061 homogalacturonan biosynthesis
BioCyc:META_PWY-822 fructan biosynthesis
BioCyc:META_PWY-6277 superpathway of 5-aminoimidazole ribonucleotide biosynthesis
BioCyc:META_PWY-7434 terminal O-glycans residues modification (via type 2 precursor disaccharide)
BioCyc:META_PWY-5705 allantoin degradation to glyoxylate III
BioCyc:META_PWY-6387 UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)
BioCyc:META_GLNSYN-PWY L-glutamine biosynthesis I
BioCyc:META_PWY2OL-4 superpathway of linalool biosynthesis
BioCyc:META_PWY-6728 methylaspartate cycle
BioCyc:META_PWY-5920 superpathway of b heme biosynthesis from glycine
BioCyc:META_PWY0-43 conversion of succinate to propanoate
BioCyc:META_PWY-3901 berberine biosynthesis
BioCyc:META_BSUBPOLYAMSYN-PWY spermidine biosynthesis I
View All Pathways