Betaine (BioCAD00000007419)
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Metabolite Card
Formula: C5H11NO2 (117.079)
SMILES: C[N+](C)(C)CC([O-])=O
Synonyms [en]
betaine; glycine betaine; trimethylammonioacetate; Trimethylaminoacetate; N,N,N-trimethylglycine; oxyneurine
Reviewed
Last reviewed on 2024-06-28.
Cite this Page
Betaine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000007419). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
The amino acid betaine derived from glycine." []
Entity Information
DBLinks
- CAS Registry Number: 107-43-7
- PubChem CID: 247
- ChEBI: 17750
- HMDB: HMDB0000043
- LipidMaps:
- KEGG: C00719
- BioCyc: BETAINE
- NCBI MeSH: Betaine
- Wikipedia: Trimethylglycine
Other DBLinks
- CAS Registry Number: 107-43-7
- CAS Registry Number: 52921-08-1
- CAS Registry Number: 590-46-5
- PubChem: 247
- ChEBI: ChEBI:17750
- HMDB: HMDB0000043
- HMDB: HMDB00043
- KEGG: C00719
- BioCyc: BETAINE
- NCBI MeSH: Betaine
- Wikipedia: Trimethylglycine
- DrugBank: DB06756
- MoNA: Alkaloids000167
- MoNA: BAF_UVA_POS000174
- MoNA: BAF_UVA_POS000650
- MoNA: BAF_UVA_POS000651
- MoNA: BAF_UVA_POS000652
- MoNA: BAF_UVA_POS000653
- MoNA: Bruker_HCD_library001555
- MoNA: CCMSLIB00000577928
- MoNA: CCMSLIB00005463947
- MoNA: CCMSLIB00005463948
- MoNA: CCMSLIB00005463949
- MoNA: CCMSLIB00005463950
- MoNA: CCMSLIB00005720375
- MoNA: EMBL-MCF_spec107285
- MoNA: EMBL-MCF_spec107314
- MoNA: EMBL-MCF_spec107448
- MoNA: EMBL_MCF_2_0_HRMS_Library000113
- MoNA: EMBL_MCF_2_0_HRMS_Library000114
- MoNA: FiehnHILIC000221
- MoNA: KO002502
- MoNA: KO002503
- MoNA: KO002504
- MoNA: KO002505
- MoNA: KO002506
- MoNA: ML004201
- MoNA: MoNA001719
- MoNA: MoNA001720
- MoNA: MoNA001721
- MoNA: MoNA010956
- MoNA: MoNA010957
- MoNA: MoNA010958
- MoNA: MoNA010959
- MoNA: MoNA016663
- MoNA: MoNA016841
- MoNA: MoNA024142
- MoNA: MoNA031940
- MoNA: MoNA031941
- MoNA: MoNA031943
- MoNA: MoNA032800
- MoNA: MoNA032801
- MoNA: MoNA032803
- MoNA: MoNA034972
- MoNA: MoNA034973
- MoNA: MoNA034974
- MoNA: MoNA035897
- MoNA: MoNA035898
- MoNA: MoNA035899
- MoNA: MoNA036528
- MoNA: MoNA036531
- MoNA: MoNA036532
- MoNA: MoNA037101
- MoNA: MoNA037102
- MoNA: MoNA037384
- MoNA: MoNA037390
- MoNA: MoNA037801
- MoNA: MoNA038134
- MoNA: MoNA038509
- MoNA: MoNA038708
- MoNA: MT000002
- MoNA: PR100443
- MoNA: PR100444
- MoNA: PS115201
- MoNA: PS115202
- MoNA: PS115203
- MoNA: PS115204
- MoNA: PS115205
- MoNA: PS115206
- MoNA: PT111520
- MoNA: PT111523
- MoNA: TOF_alkaloids_pos000135
- Metlin: METLIN_287
Class / Ontology
Metabolic Network
| ID | EC Number | Name |
|---|---|---|
| KEGG:R02565 | 1.2.1.8 | p-cumic alcohol:NAD+ oxidoreductase |
| KEGG:R02566 | 1.2.1.8 | p-cumic alcohol:NADP+ oxidoreductase |
| KEGG:R02821 | 2.1.1.5 | trimethylaminoacetate:L-homosysteine S-methyltransferase |
| KEGG:R07228 | 1.21.4.4 | acetyl-phosphate trimethylamine:thioredoxin disulfide oxidoreductase (N,N,N-trimethylglycine-forming) |
| KEGG:R07244 | 2.1.1.157 | S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase |
| KEGG:R08211 | 1.1.3.17 | betaine aldehyde:oxygen oxidoreductase |
| KEGG:R08212 | 1.1.3.17 | choline oxidase |
| KEGG:R10061 | 2.1.1.157 | S-adenosyl-L-methionine:sarcosine N-methyltransferase [betaine-forming] |
| KEGG:R10062 | 2.1.1.162 | S-adenosyl-L-methionine:glycine N-methyltransferase [betaine-forming] |
| KEGG:R12614 | 1.13.11.90 | [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate:oxygen 1R-oxidoreductase (glycine-betaine-forming) |
| KEGG:R12787 | 2.1.1.376 | glycine betaine:[Co(I) glycine betaine-specific corrinoid protein] Co-methyltransferase |
| KEGG:R13016 | 1.14.13.251 | glycine betaine,NADH:oxygen oxidoreductase (demethylating) |
| KEGG:R13307 | 3.1.2.33 | betaine-CoA hydrolase |
| BioCyc:TRANS-RXN-283 | BETAINE + ATP + WATER --> BETAINE + Pi + PROTON + ADP | |
| BioCyc:TRANS-RXN-29A | glycine betaine:proton symport | |
| BioCyc:RXN-17759 | BETAINE + 3 PROTON + 2 E- --> BETAINE-ALDEHYDE-HYDRATE | |
| BioCyc:TRANS-RXN0-490 | BETAINE<=>BETAINE | |
| BioCyc:TRANS-RXN0-532 | glycine betaine:proton antiport | |
| BioCyc:RXN0-7231 | ETR-Quinones + BETAINE-ALDEHYDE-HYDRATE --> ETR-Quinols + PROTON + BETAINE | |
| BioCyc:BADH-RXN | 1.2.1.8 | BETAINE_ALDEHYDE + NAD + WATER --> 2 PROTON + BETAINE + NADH |
Mass Spectrum
Organism Source
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| BioCyc:HUMAN_PWY66-414 | superpathway of choline degradation to L-serine |
| BioCyc:HUMAN_PWY-5328 | superpathway of methionine degradation |
| BioCyc:META_PWY-3621 | γ-butyrobetaine degradation |
| BioCyc:META_PWY-5328 | superpathway of L-methionine salvage and degradation |
| BioCyc:ECOO157_BETSYN-PWY | glycine betaine biosynthesis I (Gram-negative bacteria) |
| BioCyc:ECOO157_CHOLINE-BETAINE-ANA-PWY | choline degradation I |
| BioCyc:AGRO_BETSYN-PWY | glycine betaine biosynthesis I (Gram-negative bacteria) |
| BioCyc:AURANTIMONAS_PWY-3661 | glycine betaine degradation I |
| BioCyc:SCO_CHOLINE-BETAINE-ANA-PWY | choline degradation I |
| BioCyc:SCO_PWY-3722 | glycine betaine biosynthesis II (Gram-positive bacteria) |
| BioCyc:SCO_PWY1F-353 | glycine betaine biosynthesis III (plants) |
| BioCyc:BSUB_PWY-3722 | glycine betaine biosynthesis II (Gram-positive bacteria) |
| BioCyc:FLY_PWY-3621 | γ-butyrobetaine degradation |
| BioCyc:PCHR_CHOLINE-BETAINE-ANA-PWY | choline degradation I |
| BioCyc:THAPS_CHOLINE-BETAINE-ANA-PWY | choline degradation I |
| BioCyc:META_P541-PWY | glycine betaine biosynthesis IV (from glycine) |
| BioCyc:META_PWY-7494 | choline degradation IV |
| BioCyc:META_CHOLINE-BETAINE-ANA-PWY | choline degradation I |
| BioCyc:ECO_BETSYN-PWY | glycine betaine biosynthesis I (Gram-negative bacteria) |
| BioCyc:CAULO_CHOLINE-BETAINE-ANA-PWY | choline degradation I |