4-aminobutanoate degradation I

Dover S, Halpern YS. Utilization of ?-Aminobutyric Acid as the Sole Carbon and Nitrogen Source by Escherichia coli K-12 Mutants. J Bacteriol. 1972 Feb;109(2):835–43. doi: 10.1128/jb.109.2.835-843.1972.

Metabolites

3-Hydroxybenzaldehyde

Formula: C7H6O2 (122.0367776)

CAS ID: 100-83-4

4-Hydroxybenzaldehyde

Formula: C7H6O2 (122.0367776)

CAS ID: 123-08-0

Cadmium

Formula: Cd (113.903361)

CAS ID: 7440-43-9

Copper

Formula: Cu (62.929599)

CAS ID: 7440-50-8

Disulfiram

Formula: C10H20N2S4 (296.050928)

CAS ID: 97-77-8

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Mercury(2+)

Formula: Hg (201.970632)

CAS ID: 14302-87-5

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

Chromium

Formula: Cr (51.94051)

CAS ID: 7440-47-3

2-oxoglutarate(2-)

Formula: C5H4O5 (144.00587339999998)

CAS ID: 64-15-3

succinate(2-)

Formula: C4H4O4 (116.01095839999999)

CAS ID: 56-14-4

4-oxobutanoate

Formula: C4H5O3 (101.02386800000001)

CAS ID:

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

pyridoxal 5'-phosphate(2-)

Formula: C8H8NO6P (245.0089238)

CAS ID:



Enzyme

EC Number name full name note
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+] succinate-semialdehyde:NAD(P)+ oxidoreductase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+) succinate-semialdehyde:NAD+ oxidoreductase
1.2.1.5 aldehyde dehydrogenase [NAD(P)+] aldehyde:NAD(P)+ oxidoreductase
2.6.1.19 4-aminobutyrate-2-oxoglutarate transaminase 4-aminobutanoate:2-oxoglutarate aminotransferase
2.6.1.22 (S)-3-amino-2-methylpropionate transaminase (S)-3-amino-2-methylpropanoate:2-oxoglutarate aminotransferase


Proteins

Protein ID name full name
P23883 puuC NADP/NAD-dependent aldehyde dehydrogenase PuuC
P50457 puuE 4-aminobutyrate aminotransferase PuuE
P76149 sad Succinate semialdehyde dehydrogenase [NAD(P)+] Sad