(25S)-26-Hydroxycholest-4-en-3-one (BioCAD00000000392)

{$topic}

Metabolite Card

Formula: C27H44O2 (400.3341)
SMILES: C[C@@H](CCC[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)CO

Synonyms [en]

(25S)-26-hydroxycholest-4-en-3-one; (25S)-3-oxocholest-4-en-26-ol; (8S,9S,10R,13R,14S,17R)-17-[(2R,6S)-7-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

(25S)-26-Hydroxycholest-4-en-3-one. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000000392). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

(25S)-26-hydroxycholest-4-en-3-one is a 26-hydroxycholest-4-en-3-one in which the 25-position has S-configuration.

Entity Information

DBLinks

Other DBLinks
  • PubChem: 66932809
  • ChEBI: ChEBI:83860
  • KEGG: C20143
  • BioCyc: CPD-13887

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R09859 1.14.15.29 cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxylating)
KEGG:R11355 1.14.15.29 C20143 + 2 C00138 + 2 C00080 + C00007<=>C21304 + 2 C00139 + 2 C00001
Rhea:RHEA:31944 cholest-4-en-3-one + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+ => (25S)-3-oxocholest-4-en-26-ol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Rhea:RHEA:31945 (25S)-3-oxocholest-4-en-26-ol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O => cholest-4-en-3-one + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+
Rhea:RHEA:31946 cholest-4-en-3-one + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+ <=> (25S)-3-oxocholest-4-en-26-ol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Rhea:RHEA:51569 (25S)-3-oxocholest-4-en-26-ol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+ => (25S)-3-oxocholest-4-en-26-al + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O
Rhea:RHEA:51570 (25S)-3-oxocholest-4-en-26-al + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O => (25S)-3-oxocholest-4-en-26-ol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+
Rhea:RHEA:51571 (25S)-3-oxocholest-4-en-26-ol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+ <=> (25S)-3-oxocholest-4-en-26-al + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O
BioCyc:RXN-12850 CPD-13887 + 2 Reduced-ferredoxins + 2 PROTON + OXYGEN-MOLECULE --> CPD-13888 + 2 Oxidized-ferredoxins + 2 WATER
BioCyc:RXN-12848 CPD-323 + OXYGEN-MOLECULE + 2 Reduced-ferredoxins + 2 PROTON --> CPD-13887 + WATER + 2 Oxidized-ferredoxins
View More
Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
BioCyc:MTBH37RV_PWY-6946 cholesterol degradation to androstenedione II (cholesterol dehydrogenase)
BioCyc:META_PWY-6946 cholesterol degradation to androstenedione II (cholesterol dehydrogenase)
BioCyc:MTBH37RV_PWY-6947 superpathway of cholesterol degradation II (cholesterol dehydrogenase)
BioCyc:MTBH37RV_PWY-6945 cholesterol degradation to androstenedione I (cholesterol oxidase)
BioCyc:META_PWY-6947 superpathway of cholesterol degradation II (cholesterol dehydrogenase)
BioCyc:META_PWY-6928 superpathway of cholesterol degradation I (cholesterol oxidase)
BioCyc:META_PWY-6945 cholesterol degradation to androstenedione I (cholesterol oxidase)
View All Pathways