2-Deoxy-D-ribose 5-phosphate (BioCAD00000002452)

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Metabolite Card

Formula: C5H11O7P (214.0242)
SMILES: O[C@H]1C[C@H](O)[C@@H](COP(O)(O)=O)O1

Synonyms [en]

Deoxyribose 5-phosphate; 2-Deoxy-D-ribose 5-phosphate; 2-deoxyribose-5-phosphate; 2-deoxy-D-erythro-pentose 5-(dihydrogen phosphate); deoxyribose-5-P; {[(2R,3S,5R)-3,5-dihydroxyoxolan-2-yl]methoxy}phosphonic acid

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

2-Deoxy-D-ribose 5-phosphate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000002452). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Deoxyribose 5-phosphate is a a metabolite in the pentose phosphate pathway. It can be generated from D-glyceraldehdye-3 phosphate via the enzyme 2-Deoxyribose 5-phosphate aldolase (DERA). Alternately Deoxyribose 5-phosphate can be converted to D-glyceraldehyde-3 phosphate that can then feed into the pentose phosphate pathway. Deoxyribose 5-phosphate can also be generated from 2-Deoxy-D-ribose via the enzyme Ribokinase (EC 2.7.1.15). It has been shown in a number of organisms that deoxynucleosides or deoxyriboses cause the induction of aldolases (such as DERA) involved in their catabolism, leading to the utilisation of the pentose moiety as carbon and energy source.

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 102916-66-5
  • CAS Registry Number: 7685-50-9
  • PubChem: 150629
  • PubChem: 439288
  • PubChem: 45934311
  • ChEBI: ChEBI:16132
  • ChEBI: ChEBI:190741
  • ChEBI: ChEBI:55513
  • HMDB: HMDB0001031
  • HMDB: HMDB01031
  • KEGG: C00673
  • BioCyc: DEOXY-RIBOSE-5P
  • NCBI MeSH: 2-deoxyribose 5-phosphate
  • RefMet: RM0136032
  • MoNA: KO000564
  • MoNA: KO000565
  • MoNA: KO000566
  • MoNA: KO000567
  • MoNA: KO000568
  • MoNA: PR100525
  • MoNA: PS015002
  • MoNA: PS015007
  • MoNA: PS015009
  • Metlin: METLIN_3349
  • Metlin: METLIN_63109
  • Coconut NaturalProduct: CNP0354565.1
  • Coconut NaturalProduct: CNP0437682.1

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R01066 4.1.2.4 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming)
KEGG:R02749 5.4.2.7 2-deoxy-D-ribose 1-phosphate 1,5-phosphomutase
KEGG:R02750 2.7.1.15 ATP:2-deoxy-D-ribose 5-phosphotransferase
BioCyc:DEOXYRIBOSE-P-ALD-RXN 4.1.2.4 DEOXY-RIBOSE-5P --> GAP + ACETALD
BioCyc:D-PPENTOMUT-RXN 5.4.2.7 D-deoxyribose 1,5-phosphomutase
BioCyc:RXN-21305 3.1.4.- a-DNA-3-deoxyribose-5-phosphate + WATER --> 3-Hydroxy-Terminated-DNAs + DEOXY-RIBOSE-5P + PROTON
BioCyc:RXN-14223 2.7.1.229 2-DEOXYRIBOSE + ATP --> DEOXY-RIBOSE-5P + ADP + PROTON
BioCyc:RXN-19383 3.1.3.- DEOXY-RIBOSE-5P + WATER --> 2-DEOXYRIBOSE + Pi
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
PathBank:SMP0002089 Purine Deoxyribonucleosides Degradation
PathBank:SMP0120802 Glucose-6-phosphate Dehydrogenase Deficiency
PathBank:SMP0120585 Transaldolase Deficiency
PathBank:SMP0000520 Transaldolase Deficiency
PathBank:SMP0087246 Pentose Phosphate Pathway
PathBank:SMP0063588 Pentose Phosphate Pathway
PathBank:SMP0120584 Ribose-5-phosphate Isomerase Deficiency
PathBank:SMP0000519 Ribose-5-phosphate Isomerase Deficiency
PathBank:SMP0120804 Transaldolase Deficiency
PathBank:SMP0000031 Pentose Phosphate Pathway
PathBank:SMP0087400 Pentose Phosphate Pathway
PathBank:SMP0120803 Ribose-5-phosphate Isomerase Deficiency
PathBank:SMP0120583 Glucose-6-phosphate Dehydrogenase Deficiency
PathBank:SMP0000518 Glucose-6-phosphate Dehydrogenase Deficiency
PathBank:SMP0087339 Pentose Phosphate Pathway
PathBank:SMP0087471 Pentose Phosphate Pathway
View All Pathways