15-cis-Phytoene (BioCAD00000001952)
Metabolite Card
Formula: C40H64 (544.5008)
SMILES: CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\C=C/C=C(\C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C
Synonyms [en]
15-cis-phytoene; cis-Phytoene; Phytoene; (6E,10E,14E,16Z,18E,22E,26E)-2,6,10,14,19,23,27,31-Octamethyldotriaconta-2,6,10,14,16,18,22,26,30-nonaene; (15Z)-Phytoene; all-trans-phytoene
Last reviewed on 2024-06-28.
Cite this Page
15-cis-Phytoene. 数据之源,洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000001952). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
15-cis-Phytoene is found in cauliflower. 15-cis-Phytoene is isolated from tomato (Lycopersicon esculentum var. `Tangella'). 7,7',8,8',11,11',12,12'-Octahydrocarotene, is a carotenoid found in human fluids. Carotenoids are isoprenoid molecules that are widespread in nature and are typically seen as pigments in fruits, flowers, birds, and crustacea. Animals are unable to synthesize carotenoids de novo, and rely upon the diet as a source of these compounds. Over recent years there has been considerable interest in dietary carotenoids with respect to their potential in alleviating age-related diseases in humans. This attention has been mirrored by significant advances in cloning most of the carotenoid genes and in the genetic manipulation of crop plants with the intention of increasing levels in the diet. Studies have shown an inverse relationship between the consumption of certain fruits and vegetables and the risk of epithelial cancer. Since carotenoids are among the micronutrients found in cancer-preventive foods, detailed qualitative and quantitative determination of these compounds, particularly in fruits and vegetables and in human plasma, have recently become increasingly important (PMID: 1416048, 15003396).
DBLinks
- CAS Registry Number: 13920-14-4
- PubChem CID: 9963391
- ChEBI: 27787
- HMDB: HMDB0039093
- LipidMaps: LMPR01070255
- KEGG: C05421
- BioCyc:
- NCBI MeSH: (all-E) phytoene
- Wikipedia: Phytoene
Other DBLinks
- CAS Registry Number: 13920-14-4
- PubChem: 9963391
- ChEBI: ChEBI:27787
- HMDB: HMDB0039093
- LipidMaps: LMPR01070255
- KEGG: C05421
- NCBI MeSH: (all-E) phytoene
- Wikipedia: Phytoene
- Metlin: METLIN_41477
- Coconut NaturalProduct: CNP0186582.0
Class / Ontology
- WishartLab ClassyFire: [Tetraterpenoids] Tetraterpenoids
- LipidMaps: [C40 isoprenoids (tetraterpenes) [PR0107]] C40 isoprenoids (tetraterpenes) [PR0107]
- ChEBI: [CHEBI:27787] 15-cis-phytoene
- Coconut NaturalProduct: [Carotenoids (C40, Ψ-Ψ)] Carotenoids (C40, Ψ-Ψ)
| ID | EC Number | Name |
|---|---|---|
| KEGG:R04218 | 2.5.1.32 | prephytoene diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase |
| KEGG:R07510 | 1.14.99.- | C05421<=>C15857 |
| KEGG:R09652 | 1.3.5.5 | 15-cis-phytoene:plastoquinone oxidoreductase |
| KEGG:R09653 | 1.3.5.5 | 15-cis-phytoene:plastoquinone oxidoreductase |
| KEGG:R09691 | 1.3.99.28 | 15-cis-phytoene:acceptor oxidoreductase (neurosporene-forming) |
| KEGG:R09692 | 1.3.99.28 | 15-cis-phytoene:acceptor oxidoreductase |
| KEGG:R09693 | 1.3.99.29 | 15-cis-phytoene:acceptor oxidoreductase (zeta-carotene-forming) |
| KEGG:R09703 | 1.3.99.30 | 15-cis-phytoene:acceptor oxidoreductase (3,4-didehydrolycopene-forming) |
| KEGG:R09716 | 1.3.99.31 | 15-cis-phytoene:acceptor oxidoreductase (lycopene-forming) |
| KEGG:R10177 | 2.5.1.32 | geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase (15-cis-phytoene forming) |
| Rhea:RHEA:15586 | 1.3.99.31 | 15-cis-phytoene + 4 A => all-trans-lycopene + 4 AH2 |
| Rhea:RHEA:15587 | 1.3.99.31 | all-trans-lycopene + 4 AH2 => 15-cis-phytoene + 4 A |
| Rhea:RHEA:15588 | 1.3.99.31 | 15-cis-phytoene + 4 A <=> all-trans-lycopene + 4 AH2 |
| Rhea:RHEA:30176 | 1.3.5.5 | 2 plastoquinone-9 + 15-cis-phytoene => 2 plastoquinol-9 + 9,9',15-tri-cis-ζ-carotene |
| Rhea:RHEA:30177 | 1.3.5.5 | 2 plastoquinol-9 + 9,9',15-tri-cis-ζ-carotene => 2 plastoquinone-9 + 15-cis-phytoene |
| Rhea:RHEA:30178 | 1.3.5.5 | 2 plastoquinone-9 + 15-cis-phytoene <=> 2 plastoquinol-9 + 9,9',15-tri-cis-ζ-carotene |
| Rhea:RHEA:30192 | plastoquinone-9 + 15-cis-phytoene => 15,9'-di-cis-phytofluene + plastoquinol-9 | |
| Rhea:RHEA:30193 | 15,9'-di-cis-phytofluene + plastoquinol-9 => plastoquinone-9 + 15-cis-phytoene | |
| Rhea:RHEA:30194 | plastoquinone-9 + 15-cis-phytoene <=> 15,9'-di-cis-phytofluene + plastoquinol-9 | |
| Rhea:RHEA:30288 | 1.3.5.5 | 2 a plastoquinone + 15-cis-phytoene => 9,9',15-tri-cis-ζ-carotene + 2 a plastoquinol |
Taxonomy Source
- Acacia adunca [ncbi taxid: 204988]
- Adiantum lunulatum [ncbi taxid: ]
- Agrobacterium aurantiacum [ncbi taxid: 44155]
- Alstonia spathulata [ncbi taxid: ]
- Amathia pinnata [ncbi taxid: ]
- Anacystis montana [ncbi taxid: ]
- Annona cornifolia [ncbi taxid: 502529]
- Arabidopsis thaliana [ncbi taxid: 3702]
- Artemisia assoana [ncbi taxid: 1227617]
- Asterospicularia laurae [ncbi taxid: 1540332]
- Astragalus sempervirens [ncbi taxid: 1532287]
- Bishovia boliviensis [ncbi taxid: ]
- Blastochloris viridis [ncbi taxid: 1079]
- Brassica oleracea L.var.Botrytis [ncbi taxid: ]
- Calostephane divaricata [ncbi taxid: 1548555]
- Caragana aurantiaca [ncbi taxid: 626687]
- Carica papaya [ncbi taxid: 3649]
- Chaenomeles sinensis [ncbi taxid: ]
- Citrullus lanatus [ncbi taxid: 3654]
- Citrus aurantium [ncbi taxid: ]
- Citrus natsudaidai [ncbi taxid: 109792]
- Citrus reticulata [ncbi taxid: 85571]
- Citrus sinensis [ncbi taxid: 2711]
- Citrus sinensis L. Osbeck [ncbi taxid: ]
- Citrus trifoliata [ncbi taxid: 37690]
- Coccinella septempunctata [ncbi taxid: 41139]
- Cotyledon secunda [ncbi taxid: ]
- Crocus sativus [ncbi taxid: 82528]
- Drechslera avenae [ncbi taxid: 33199]
- Dumortiera hirsuta [ncbi taxid: 56917]
- Erwinia herbicola strain Eho10 [ncbi taxid: ]
- Erwinia herbicola strain Eho13 [ncbi taxid: ]
- Erwinia uredovora [ncbi taxid: ]
- Eucalyptus melliodora [ncbi taxid: 183838]
- Flavobacterium sp. Strain R1534 [ncbi taxid: ]
- Gnetum latifolium [ncbi taxid: 225592]
- Goniothalamus malayanus [ncbi taxid: 261094]
- Halobacterium cutirubrum [ncbi taxid: ]
- Hedysarum connatum [ncbi taxid: ]
- Helipterum roseum [ncbi taxid: ]
- Homo sapiens [ncbi taxid: 9606]
- Hypericum laricifolium [ncbi taxid: 1136989]
- Ipomoea batatas [ncbi taxid: 4120]
- Ipomoea digitata [ncbi taxid: ]
- Laurencia spectabilis [ncbi taxid: ]
- Leathesia nana [ncbi taxid: ]
- Lepisorus ussuriensis [ncbi taxid: 699700]
- Lycopersicon esculentum var.(Tangella). [ncbi taxid: ]
- Lysimachia mauritiana [ncbi taxid: 306286]
- Marrubium anisodon [ncbi taxid: 2291693]
- Myxococcus xanthus [ncbi taxid: 34]
- Nasutitermes ephratae [ncbi taxid: 114633]
- Naucleopsis ternstroemiiflora [ncbi taxid: 241899]
- Neurospora crassa YLO [ncbi taxid: ]
- Ononis spinosa [ncbi taxid: 58890]
- Passiflora edulis [ncbi taxid: 78168]
- Pastinaca sativa [ncbi taxid: 4041]
- Peltostigma guatemalense [ncbi taxid: 1136780]
- Phoebe pittieri [ncbi taxid: ]
- Premna odorata [ncbi taxid: 1037421]
- Pseudoalteromonas luteoviolacea [ncbi taxid: 43657]
- Rauvolfia vomitoria [ncbi taxid: 403115]
- Rhodobacter capsulatus [ncbi taxid: 1061]
- Rhodobacter sphaeroides [ncbi taxid: ]
- Rhodotorula minuta [ncbi taxid: ]
- Rumex maritimus [ncbi taxid: 467604]
- Sabina sargentii [ncbi taxid: ]
- Salvia syriaca [ncbi taxid: 1685717]
- Scenedesmus acutus [ncbi taxid: 104103]
- Scutellaria amoena [ncbi taxid: 1052904]
- Sinularia depressa [ncbi taxid: ]
- Solanum laxum [ncbi taxid: 205558]
- Solanum lycopersicum [ncbi taxid: 4081]
- Stigma croci [ncbi taxid: ]
- Streptomyces avermectinius [ncbi taxid: ]
- Streptomyces griseus [ncbi taxid: 1911]
- Swertia franchetiana [ncbi taxid: 50785]
- Synechococcus sp. strain PCC7942 [ncbi taxid: ]
- Synechocystis sp. strain PC6803 [ncbi taxid: ]
- Tagetes erecta [ncbi taxid: 13708]
- Tecoma stans [ncbi taxid: 69904]
- Thermus thermophilus [ncbi taxid: 274]
- Vaccinium oxycoccos [ncbi taxid: 516948]
- Viguiera incana [ncbi taxid: 1048928]
- Vitis vinifera [ncbi taxid: 29760]
- Wikstroemia retusa [ncbi taxid: 1872696]
- Zanthoxylum tetraspermum [ncbi taxid: ]
Pathway Synthetic
| pathway id | name |
|---|---|
| BioCyc:META_PWY-6287 | neurosporene biosynthesis |
| BioCyc:ARA_PWY-6287 | neurosporene biosynthesis |
| BioCyc:SYNEL_PWY-6475 | trans-lycopene biosynthesis II (plants) |
| BioCyc:META_CAROTENOID-PWY | superpathway of carotenoid biosynthesis in plants |
| BioCyc:SCO_PWY-6475 | trans-lycopene biosynthesis II (plants) |
| BioCyc:PABTQVLC_PWY-5942 | trans-lycopene biosynthesis I (bacteria) |
| BioCyc:SCO_CAROTENOID-PWY | superpathway of carotenoid biosynthesis |
| BioCyc:THAPS_PWY-6287 | neurosporene biosynthesis |
| BioCyc:THAPS_PWY-5942 | trans-lycopene biosynthesis I (bacteria) |
| BioCyc:PABTQVLC_PWY-6287 | neurosporene biosynthesis |
| BioCyc:CORYNE_PWY-6287 | neurosporene biosynthesis |
| BioCyc:CORYNE_PWY-5942 | trans-lycopene biosynthesis I (bacteria) |
| BioCyc:META_PWY-7393 | β-carotene biosynthesis (engineered) |
| BioCyc:META_PWY-5942 | trans-lycopene biosynthesis I |
| BioCyc:META_PWY-6475 | trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria) |
| BioCyc:ARA_PWY-6475 | trans-lycopene biosynthesis II (plants) |
| PlantCyc:SOY_PWY-6475 | trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria) |
| PlantCyc:SPENNELLII_PWY-6475 | trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria) |
| PlantCyc:SUGARBEET_PWY-6287 | neurosporene biosynthesis |
| PlantCyc:AHALLERI_PWY-6475 | trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria) |