15-cis-Phytoene (BioCAD00000001952)

plant natural products microbial natural products

Metabolite Card

Formula: C40H64 (544.5008)
SMILES: CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\C=C/C=C(\C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C

Synonyms [en]

15-cis-phytoene; cis-Phytoene; Phytoene; (6E,10E,14E,16Z,18E,22E,26E)-2,6,10,14,19,23,27,31-Octamethyldotriaconta-2,6,10,14,16,18,22,26,30-nonaene; (15Z)-Phytoene; all-trans-phytoene

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

15-cis-Phytoene. 数据之源,洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000001952). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

15-cis-Phytoene is found in cauliflower. 15-cis-Phytoene is isolated from tomato (Lycopersicon esculentum var. `Tangella'). 7,7',8,8',11,11',12,12'-Octahydrocarotene, is a carotenoid found in human fluids. Carotenoids are isoprenoid molecules that are widespread in nature and are typically seen as pigments in fruits, flowers, birds, and crustacea. Animals are unable to synthesize carotenoids de novo, and rely upon the diet as a source of these compounds. Over recent years there has been considerable interest in dietary carotenoids with respect to their potential in alleviating age-related diseases in humans. This attention has been mirrored by significant advances in cloning most of the carotenoid genes and in the genetic manipulation of crop plants with the intention of increasing levels in the diet. Studies have shown an inverse relationship between the consumption of certain fruits and vegetables and the risk of epithelial cancer. Since carotenoids are among the micronutrients found in cancer-preventive foods, detailed qualitative and quantitative determination of these compounds, particularly in fruits and vegetables and in human plasma, have recently become increasingly important (PMID: 1416048, 15003396).

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 13920-14-4
  • PubChem: 9963391
  • ChEBI: ChEBI:27787
  • HMDB: HMDB0039093
  • LipidMaps: LMPR01070255
  • KEGG: C05421
  • NCBI MeSH: (all-E) phytoene
  • Wikipedia: Phytoene
  • Metlin: METLIN_41477
  • Coconut NaturalProduct: CNP0186582.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R04218 2.5.1.32 prephytoene diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase
KEGG:R07510 1.14.99.- C05421<=>C15857
KEGG:R09652 1.3.5.5 15-cis-phytoene:plastoquinone oxidoreductase
KEGG:R09653 1.3.5.5 15-cis-phytoene:plastoquinone oxidoreductase
KEGG:R09691 1.3.99.28 15-cis-phytoene:acceptor oxidoreductase (neurosporene-forming)
KEGG:R09692 1.3.99.28 15-cis-phytoene:acceptor oxidoreductase
KEGG:R09693 1.3.99.29 15-cis-phytoene:acceptor oxidoreductase (zeta-carotene-forming)
KEGG:R09703 1.3.99.30 15-cis-phytoene:acceptor oxidoreductase (3,4-didehydrolycopene-forming)
KEGG:R09716 1.3.99.31 15-cis-phytoene:acceptor oxidoreductase (lycopene-forming)
KEGG:R10177 2.5.1.32 geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase (15-cis-phytoene forming)
Rhea:RHEA:15586 1.3.99.31 15-cis-phytoene + 4 A => all-trans-lycopene + 4 AH2
Rhea:RHEA:15587 1.3.99.31 all-trans-lycopene + 4 AH2 => 15-cis-phytoene + 4 A
Rhea:RHEA:15588 1.3.99.31 15-cis-phytoene + 4 A <=> all-trans-lycopene + 4 AH2
Rhea:RHEA:30176 1.3.5.5 2 plastoquinone-9 + 15-cis-phytoene => 2 plastoquinol-9 + 9,9',15-tri-cis-ζ-carotene
Rhea:RHEA:30177 1.3.5.5 2 plastoquinol-9 + 9,9',15-tri-cis-ζ-carotene => 2 plastoquinone-9 + 15-cis-phytoene
Rhea:RHEA:30178 1.3.5.5 2 plastoquinone-9 + 15-cis-phytoene <=> 2 plastoquinol-9 + 9,9',15-tri-cis-ζ-carotene
Rhea:RHEA:30192 plastoquinone-9 + 15-cis-phytoene => 15,9'-di-cis-phytofluene + plastoquinol-9
Rhea:RHEA:30193 15,9'-di-cis-phytofluene + plastoquinol-9 => plastoquinone-9 + 15-cis-phytoene
Rhea:RHEA:30194 plastoquinone-9 + 15-cis-phytoene <=> 15,9'-di-cis-phytofluene + plastoquinol-9
Rhea:RHEA:30288 1.3.5.5 2 a plastoquinone + 15-cis-phytoene => 9,9',15-tri-cis-ζ-carotene + 2 a plastoquinol
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Organism Source

Taxonomy Source

  1. Acacia adunca [ncbi taxid: 204988]
  2. Adiantum lunulatum [ncbi taxid: ]
  3. Agrobacterium aurantiacum [ncbi taxid: 44155]
  4. Alstonia spathulata [ncbi taxid: ]
  5. Amathia pinnata [ncbi taxid: ]
  6. Anacystis montana [ncbi taxid: ]
  7. Annona cornifolia [ncbi taxid: 502529]
  8. Arabidopsis thaliana [ncbi taxid: 3702]
  9. Artemisia assoana [ncbi taxid: 1227617]
  10. Asterospicularia laurae [ncbi taxid: 1540332]
  11. Astragalus sempervirens [ncbi taxid: 1532287]
  12. Bishovia boliviensis [ncbi taxid: ]
  13. Blastochloris viridis [ncbi taxid: 1079]
  14. Brassica oleracea L.var.Botrytis [ncbi taxid: ]
  15. Calostephane divaricata [ncbi taxid: 1548555]
  16. Caragana aurantiaca [ncbi taxid: 626687]
  17. Carica papaya [ncbi taxid: 3649]
  18. Chaenomeles sinensis [ncbi taxid: ]
  19. Citrullus lanatus [ncbi taxid: 3654]
  20. Citrus aurantium [ncbi taxid: ]
  21. Citrus natsudaidai [ncbi taxid: 109792]
  22. Citrus reticulata [ncbi taxid: 85571]
  23. Citrus sinensis [ncbi taxid: 2711]
  24. Citrus sinensis L. Osbeck [ncbi taxid: ]
  25. Citrus trifoliata [ncbi taxid: 37690]
  26. Coccinella septempunctata [ncbi taxid: 41139]
  27. Cotyledon secunda [ncbi taxid: ]
  28. Crocus sativus [ncbi taxid: 82528]
  29. Drechslera avenae [ncbi taxid: 33199]
  30. Dumortiera hirsuta [ncbi taxid: 56917]
  31. Erwinia herbicola strain Eho10 [ncbi taxid: ]
  32. Erwinia herbicola strain Eho13 [ncbi taxid: ]
  33. Erwinia uredovora [ncbi taxid: ]
  34. Eucalyptus melliodora [ncbi taxid: 183838]
  35. Flavobacterium sp. Strain R1534 [ncbi taxid: ]
  36. Gnetum latifolium [ncbi taxid: 225592]
  37. Goniothalamus malayanus [ncbi taxid: 261094]
  38. Halobacterium cutirubrum [ncbi taxid: ]
  39. Hedysarum connatum [ncbi taxid: ]
  40. Helipterum roseum [ncbi taxid: ]
  41. Homo sapiens [ncbi taxid: 9606]
  42. Hypericum laricifolium [ncbi taxid: 1136989]
  43. Ipomoea batatas [ncbi taxid: 4120]
  44. Ipomoea digitata [ncbi taxid: ]
  45. Laurencia spectabilis [ncbi taxid: ]
  46. Leathesia nana [ncbi taxid: ]
  47. Lepisorus ussuriensis [ncbi taxid: 699700]
  48. Lycopersicon esculentum var.(Tangella). [ncbi taxid: ]
  49. Lysimachia mauritiana [ncbi taxid: 306286]
  50. Marrubium anisodon [ncbi taxid: 2291693]
  51. Myxococcus xanthus [ncbi taxid: 34]
  52. Nasutitermes ephratae [ncbi taxid: 114633]
  53. Naucleopsis ternstroemiiflora [ncbi taxid: 241899]
  54. Neurospora crassa YLO [ncbi taxid: ]
  55. Ononis spinosa [ncbi taxid: 58890]
  56. Passiflora edulis [ncbi taxid: 78168]
  57. Pastinaca sativa [ncbi taxid: 4041]
  58. Peltostigma guatemalense [ncbi taxid: 1136780]
  59. Phoebe pittieri [ncbi taxid: ]
  60. Premna odorata [ncbi taxid: 1037421]
  61. Pseudoalteromonas luteoviolacea [ncbi taxid: 43657]
  62. Rauvolfia vomitoria [ncbi taxid: 403115]
  63. Rhodobacter capsulatus [ncbi taxid: 1061]
  64. Rhodobacter sphaeroides [ncbi taxid: ]
  65. Rhodotorula minuta [ncbi taxid: ]
  66. Rumex maritimus [ncbi taxid: 467604]
  67. Sabina sargentii [ncbi taxid: ]
  68. Salvia syriaca [ncbi taxid: 1685717]
  69. Scenedesmus acutus [ncbi taxid: 104103]
  70. Scutellaria amoena [ncbi taxid: 1052904]
  71. Sinularia depressa [ncbi taxid: ]
  72. Solanum laxum [ncbi taxid: 205558]
  73. Solanum lycopersicum [ncbi taxid: 4081]
  74. Stigma croci [ncbi taxid: ]
  75. Streptomyces avermectinius [ncbi taxid: ]
  76. Streptomyces griseus [ncbi taxid: 1911]
  77. Swertia franchetiana [ncbi taxid: 50785]
  78. Synechococcus sp. strain PCC7942 [ncbi taxid: ]
  79. Synechocystis sp. strain PC6803 [ncbi taxid: ]
  80. Tagetes erecta [ncbi taxid: 13708]
  81. Tecoma stans [ncbi taxid: 69904]
  82. Thermus thermophilus [ncbi taxid: 274]
  83. Vaccinium oxycoccos [ncbi taxid: 516948]
  84. Viguiera incana [ncbi taxid: 1048928]
  85. Vitis vinifera [ncbi taxid: 29760]
  86. Wikstroemia retusa [ncbi taxid: 1872696]
  87. Zanthoxylum tetraspermum [ncbi taxid: ]

Pathway Synthetic

pathway id name
BioCyc:META_PWY-6287 neurosporene biosynthesis
BioCyc:ARA_PWY-6287 neurosporene biosynthesis
BioCyc:SYNEL_PWY-6475 trans-lycopene biosynthesis II (plants)
BioCyc:META_CAROTENOID-PWY superpathway of carotenoid biosynthesis in plants
BioCyc:SCO_PWY-6475 trans-lycopene biosynthesis II (plants)
BioCyc:PABTQVLC_PWY-5942 trans-lycopene biosynthesis I (bacteria)
BioCyc:SCO_CAROTENOID-PWY superpathway of carotenoid biosynthesis
BioCyc:THAPS_PWY-6287 neurosporene biosynthesis
BioCyc:THAPS_PWY-5942 trans-lycopene biosynthesis I (bacteria)
BioCyc:PABTQVLC_PWY-6287 neurosporene biosynthesis
BioCyc:CORYNE_PWY-6287 neurosporene biosynthesis
BioCyc:CORYNE_PWY-5942 trans-lycopene biosynthesis I (bacteria)
BioCyc:META_PWY-7393 β-carotene biosynthesis (engineered)
BioCyc:META_PWY-5942 trans-lycopene biosynthesis I
BioCyc:META_PWY-6475 trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria)
BioCyc:ARA_PWY-6475 trans-lycopene biosynthesis II (plants)
PlantCyc:SOY_PWY-6475 trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria)
PlantCyc:SPENNELLII_PWY-6475 trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria)
PlantCyc:SUGARBEET_PWY-6287 neurosporene biosynthesis
PlantCyc:AHALLERI_PWY-6475 trans-lycopene biosynthesis II (oxygenic phototrophs and green sulfur bacteria)
View All Pathways