trans-lycopene biosynthesis II (plants)

Chen Y, Li F, Wurtzel ET. Isolation and Characterization of the Z-ISO Gene Encoding a Missing Component of Carotenoid Biosynthesis in Plants . 2010 Mar 24;153(1):66–79. doi: 10.1104/pp.110.153916.; Sandmann G. Evolution of carotene desaturation: The complication of a simple pathway. Archives of Biochemistry and Biophysics. 2009 Mar;483(2):169–74. doi: 10.1016/j.abb.2008.10.004.; Li F, Murillo C, Wurtzel ET. Maize Y9 Encodes a Product Essential for 15-cis-?-Carotene Isomerization. 2007 Apr 13;144(2):1181–9. doi: 10.1104/pp.107.098996.; Isaacson T, Ohad I, Beyer P, Hirschberg J. Analysis in vitro of the enzyme CRTISO establishes a poly-cis-carotenoid biosynthesis pathway in plants. Plant Physiol. 2004 Dec;136(4):4246–55. PMID: 15557094; PMCID: PMC535854.; Breitenbach J, Sandmann G. zeta-Carotene cis isomers as products and substrates in the plant poly-cis carotenoid biosynthetic pathway to lycopene. Planta. 2005 Mar;220(5):785–93. doi: 10.1007/s00425-004-1395-2. PMID: 15503129.

Metabolites

15-cis-Phytoene

Formula: C40H64 (544.5007744)

CAS ID: 13920-14-4

15,9'-dicis-Phytofluene

Formula: C40H62 (542.4851252)

CAS ID: 72746-34-0

7,9,7',9'-tetracis-Lycopene

Formula: C40H56 (536.4381776)

CAS ID: 2361-24-2

7,9,9'-tricis-Neurosporene

Formula: C40H58 (538.4538268)

CAS ID: 10467-46-6

9,9'-dicis-zeta-Carotene

Formula: C40H60 (540.469476)

CAS ID: 72746-33-9

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3

Lycopene

Formula: C40H56 (536.4381776)

CAS ID: 502-65-8



Enzyme

EC Number name full name note
1.3.5.6 9,9'-dicis-zeta-carotene desaturase 9,9'-dicis-zeta-corotene:quinone oxidoreductase
2.5.1.32 15-cis-phytoene synthase geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase (15-cis-phytoene forming)
5.2.1.13 prolycopene isomerase 7,9,7',9'-tetracis-lycopene cis-trans-isomerase


Proteins

Protein ID name full name