neurosporene biosynthesis

Stickforth P, Sandmann G. Structural and kinetics properties of a mutated phytoene desaturase from Rubrivivax gelatinosus with modified product specificity. Archives of Biochemistry and Biophysics. 2011 Jan;505(1):118–22. doi: 10.1016/j.abb.2010.09.021.; Wang C, Liao JC. Alteration of Product Specificity of Rhodobacter sphaeroides Phytoene Desaturase by Directed Evolution. Journal of Biological Chemistry. 2001 Nov;276(44):41161–4. doi: 10.1074/jbc.m105786200.; Bartley GE, Scolnik PA, Beyer P. Two Arabidopsis thaliana carotene desaturases, phytoene desaturase and ?-carotene desaturase, expressed in Escherichia coli, catalyze a poly-cis pathway to yield pro-lycopene. European Journal of Biochemistry. 1999 Jan;259(1-2):396–403. doi: 10.1046/j.1432-1327.1999.00051.x.; Raisig A, Bartley G, Scolnik P, Sandmann G. Purification in an Active State and Properties of the 3-Step Phytoene Desaturase from Rhodobacter capsulatus Overexpressed in Escherichia coil. Journal of Biochemistry. 1996 Mar 01;119(3):559–64. doi: 10.1093/oxfordjournals.jbchem.a021278.

Metabolites

15-cis-Phytoene

Formula: C40H64 (544.5007744)

CAS ID: 13920-14-4

all-trans-Neurosporene

Formula: C40H58 (538.4538268)

CAS ID: 502-64-7

all-trans-Phytofluene

Formula: C40H62 (542.4851252)

CAS ID: 27664-65-9

all-trans-zeta-Carotene

Formula: C40H60 (540.469476)

CAS ID: 13587-06-9

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3



Enzyme

EC Number name full name note


Proteins

Protein ID name full name