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Metabolite Card

Note

Tetranitromethane appears as a pale yellow liquid. Irritates skin and respiratory tract. Very toxic by inhalation. Difficult to ignite. Burns at a steady rate once ignited. Under prolonged exposure to fire or heat containers may rupture violently and rocket Produces toxic oxides of nitrogen during combustion. Tetranitromethane is an organonitrogen compound. Tetranitromethane is a synthetic, oily, colorless to pale yellow liquid that is insoluble in water and soluble in alcohol and ether. Tetranitromethane is used as an oxidizing agent in rocket propellants and explosives as well as an additive to increase the cetane number of diesel fuel. In science, it is used as both an analytical reagent for the detection of double bonds in organic compounds and as a mild nitrating reagent that reacts with tyrosine residues in proteins. The primary route of potential human exposure to tetranitromethane is inhalation. Acute inhalation exposure to tetranitromethane can result in irritation of the respiratory tract, buildup of fluid in the lungs (pulmonary edema) and interference with the oxygen-carrying capacity of red blood cells (methemoglobinemia). Contact with this compound can cause irritation of the eyes and skin. It is reasonably anticipated to be a human carcinogen. (NCI05) Tetranitromethane can cause cancer according to The National Toxicology Program. Corrosive oxidant, explosive; additive to diesel and rocket fuels; causes skin and lung irritation; proposed war gas. A useful reagent for studying the modification of specific amino acids, particularly tyrosine residues in proteins. Has also been used for studying carbanion formation and for detecting the presence of double bonds in organic compounds.