Rifampicin (BioCAD00000017298)

blood

Metabolite Card

Formula: C43H58N4O12 (822.4051)
SMILES: CO[C@H]1\\C=C\\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)\\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(\\C=N\\N1CCN(C)CC1)c(O)c4c3C2=O

Synonyms [en]

Rifampicin; rifampin; rifamcin; 3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV; Rifampicina; Rifampicinum

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Rifampicin. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000017298). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

A member of the class of rifamycins that is a a semisynthetic antibiotic derived from Amycolatopsis rifamycinica (previously known as Amycolatopsis mediterranei and Streptomyces mediterranei)." []

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 13292-46-1
  • CAS Registry Number: Rifampicin - CAS 13292-46-1
  • PubChem: 135398735
  • PubChem: 135441414
  • PubChem: 135449527
  • PubChem: 135476790
  • PubChem: 135512673
  • PubChem: 135550179
  • PubChem: 135876149
  • PubChem: 135900090
  • PubChem: 135921123
  • PubChem: 135921134
  • PubChem: 135925261
  • PubChem: 135925741
  • PubChem: 135932822
  • PubChem: 136122621
  • PubChem: 136246612
  • PubChem: 136601293
  • PubChem: 136619758
  • PubChem: 137286743
  • PubChem: 137287990
  • PubChem: 154075449
  • PubChem: 5381226
  • ChEBI: ChEBI:28077
  • HMDB: HMDB0015179
  • HMDB: HMDB0257225
  • KEGG: C06688
  • BioCyc: CPD-18727
  • NCBI MeSH: Rifampin
  • Wikipedia: Rifampicin
  • DrugBank: DB01045
  • RefMet: RM0139049
  • MoNA: BML82085
  • MoNA: BML82086
  • MoNA: BML82088
  • MoNA: CCMSLIB00000076971
  • MoNA: CE000181
  • MoNA: CE000182
  • MoNA: CE000183
  • MoNA: CE000184
  • MoNA: CE000185
  • MoNA: PB005805
  • MoNA: PB005806
  • MoNA: PB005807
  • Coconut NaturalProduct: CNP0030878.1
  • Coconut NaturalProduct: CNP0030878.2
  • Coconut NaturalProduct: CNP0257409.1
  • Coconut NaturalProduct: CNP0336835.1
  • Coconut NaturalProduct: CNP0336835.2
  • Coconut NaturalProduct: CNP0375539.1

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R11151 1.14.13.211 rifampicin:NADH:oxygen oxidoreductase (2-hydroxy-2,27-secorifampicin-forming; ring-cleaving)
KEGG:R11152 1.14.13.211 rifampicin:NADPH:oxygen oxidoreductase (2'-N-hydroxyrifampicin-forming)
KEGG:R11964 2.7.9.6 ATP:rifampicin, water 21-O-phosphotransferase
BioCyc:RXN-17329 1.14.13.211 CPD-18727 + OXYGEN-MOLECULE + NADH-P-OR-NOP --> CPD-18728 + NAD-P-OR-NOP + WATER
BioCyc:RXN-18733 2.7.9.6 CPD-18727 + ATP + WATER --> CPD-20026 + AMP + Pi + 2 PROTON
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Organism Source

Taxonomy Source

  1. Streptomyces mediterranei [ncbi taxid: ]

Pathway Synthetic

pathway id name
Reactome:R-BTA-597592 Post-translational protein modification
Reactome:R-BTA-2990846 SUMOylation
Reactome:R-BTA-4090294 SUMOylation of intracellular receptors
Reactome:R-DRE-392499 Metabolism of proteins
Reactome:R-DME-597592 Post-translational protein modification
Reactome:R-DME-3108232 SUMO E3 ligases SUMOylate target proteins
Reactome:R-HSA-392499 Metabolism of proteins
Reactome:R-HSA-597592 Post-translational protein modification
Reactome:R-HSA-2990846 SUMOylation
Reactome:R-HSA-4090294 SUMOylation of intracellular receptors
Reactome:R-RNO-597592 Post-translational protein modification
Reactome:R-RNO-2990846 SUMOylation
Reactome:R-RNO-4090294 SUMOylation of intracellular receptors
Reactome:R-XTR-3108232 SUMO E3 ligases SUMOylate target proteins
Reactome:R-RNO-392499 Metabolism of proteins
Reactome:R-SSC-392499 Metabolism of proteins
Reactome:R-SSC-3108232 SUMO E3 ligases SUMOylate target proteins
Reactome:R-XTR-597592 Post-translational protein modification
Reactome:R-XTR-2990846 SUMOylation
Reactome:R-XTR-4090294 SUMOylation of intracellular receptors
View All Pathways