SUMOylation

Hay RT. Decoding the SUMO signal. Biochem Soc Trans. 2013 Apr;41(2):463–73. doi: 10.1042/bst20130015. PMID: 23514139.; Hannoun Z, Greenhough S, Jaffray E, Hay RT, Hay DC. Post-translational modification by SUMO. Toxicology. 2010 Dec 30;278(3):288–93. doi: 10.1016/j.tox.2010.07.013. PMID: 20674646.; Gareau JR, Lima CD. The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition. Nature Reviews Molecular Cell Biology. 2010 Nov 23;11(12):861–71. doi: 10.1038/nrm3011.; Wilkinson KA, Henley JM. Mechanisms, regulation and consequences of protein SUMOylation. Biochem J. 2010 May 13;428(2):133–45. PMID: 20462400; PMCID: PMC3310159.; Wang Y, Dasso M. SUMOylation and deSUMOylation at a glance. J Cell Sci. 2009 Dec 01;122(Pt 23):4249–52. PMID: 19923268; PMCID: PMC2779127.; Hay RT. SUMO-specific proteases: a twist in the tail. Trends Cell Biol. 2007 Aug;17(8):370–6. doi: 10.1016/j.tcb.2007.08.002. PMID: 17768054.

Metabolites

Rifampicin

Formula: C43H58N4O12 (822.4051028)

CAS ID: 13292-46-1

adenosine 5'-monophosphate(2-)

Formula: C10H12N5O7P (345.0474332)

CAS ID:

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:



Enzyme

EC Number name full name note
1.1.1.-
2.1.1.37 DNA (cytosine-5-)-methyltransferase S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase
2.3.2.27 RING-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type)
2.4.2.30 NAD+ ADP-ribosyltransferase NAD+:poly(ADP-D-ribosyl)-acceptor ADP-D-ribosyl-transferase
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)
3.5.1.124 protein deglycase a [protein]-L-amino acid-1-hydroxypropan-2-one hydrolase [(R)-lactate-forming]
3.5.1.98 histone deacetylase histone amidohydrolase
5.6.2.1 DNA topoisomerase DNA topoisomerase
5.6.2.2 DNA topoisomerase (ATP-hydrolysing) DNA topoisomerase (ATP-hydrolysing)


Proteins

Protein ID name full name