Phenylethyl alcohol (BioCAD00000016177)

feces

Metabolite Card

Formula: C8H10O (122.0732)
SMILES: OCCC1=CC=CC=C1

Synonyms [en]

2-Phenylethanol; Phenylethyl alcohol; Benzeneethanol; Phenethyl alcohol; Benzylmethanol; 2-PHENYL-ETHANOL

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Phenylethyl alcohol. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000016177). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

2-Phenylethanol, also known as benzeneethanol or benzyl carbinol, belongs to the class of organic compounds known as benzene and substituted derivatives. These are aromatic compounds containing one monocyclic ring system consisting of benzene. 2-Phenylethanol exists in all living species, ranging from bacteria to humans. 2-Phenylethanol is a bitter, floral, and honey tasting compound. 2-Phenylethanol is found, on average, in the highest concentration within a few different foods, such as red wines, black walnuts, and white wines and in a lower concentration in grape wines, sweet basils, and peppermints. 2-Phenylethanol has also been detected, but not quantified, in several different foods, such as asparagus, allspices, fruits, horned melons, and lemons. 2-Phenylethanol, with regard to humans, has been found to be associated with several diseases such as ulcerative colitis, pervasive developmental disorder not otherwise specified, and autism. 2-phenylethanol has also been linked to the inborn metabolic disorder celiac disease. A primary alcohol that is ethanol substituted by a phenyl group at position 2.

Cytoplasm Extracellular
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 1321-27-3
  • CAS Registry Number: 19601-20-8
  • CAS Registry Number: 60-12-8
  • PubChem: 6054
  • ChEBI: ChEBI:49000
  • HMDB: HMDB0033944
  • HMDB: HMDB33944
  • KEGG: C05853
  • BioCyc: CPD-7035
  • NCBI MeSH: Phenylethyl Alcohol
  • Wikipedia: Phenethyl_alcohol
  • DrugBank: DB02192
  • RefMet: RM0016767
  • MoNA: FiehnLibVolatile0031
  • MoNA: HMDB0033944_c_ms_101455
  • MoNA: HMDB0033944_c_ms_101456
  • MoNA: HMDB0033944_c_ms_101457
  • MoNA: JP000994
  • MoNA: JP001564
  • MoNA: JP005825
  • MoNA: JP006570
  • Metlin: METLIN_64740
  • Coconut NaturalProduct: CNP0402269.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R02611 1.1.1.90 phenylethylalcohol:NAD+ oxidoreductase
Rhea:RHEA:63737 2-phenylacetaldehyde + NADPH + H+ => 2-phenylethanol + NADP+
Rhea:RHEA:63738 2-phenylethanol + NADP+ => 2-phenylacetaldehyde + NADPH + H+
Rhea:RHEA:63739 2-phenylacetaldehyde + NADPH + H+ <=> 2-phenylethanol + NADP+
Rhea:RHEA:63741 2-phenylacetaldehyde + NADH + H+ => 2-phenylethanol + NAD+
Rhea:RHEA:63742 2-phenylethanol + NAD+ => 2-phenylacetaldehyde + NADH + H+
Rhea:RHEA:63743 2-phenylacetaldehyde + NADH + H+ <=> 2-phenylethanol + NAD+
Rhea:RHEA:64837 2-phenylethanol + acetyl-CoA => phenethyl acetate + CoA
Rhea:RHEA:64838 phenethyl acetate + CoA => 2-phenylethanol + acetyl-CoA
Rhea:RHEA:64839 2-phenylethanol + acetyl-CoA <=> phenethyl acetate + CoA
Rhea:RHEA:64841 2-phenylethanol + benzoyl-CoA => phenethyl benzoate + CoA
Rhea:RHEA:64842 phenethyl benzoate + CoA => 2-phenylethanol + benzoyl-CoA
Rhea:RHEA:64843 2-phenylethanol + benzoyl-CoA <=> phenethyl benzoate + CoA
Rhea:RHEA:79320 2-phenylethanol + 2 Fe(III)-[cytochrome c] => 2-phenylacetaldehyde + 2 Fe(II)-[cytochrome c] + 2 H+
Rhea:RHEA:79321 2-phenylacetaldehyde + 2 Fe(II)-[cytochrome c] + 2 H+ => 2-phenylethanol + 2 Fe(III)-[cytochrome c]
Rhea:RHEA:79322 2-phenylethanol + 2 Fe(III)-[cytochrome c] <=> 2-phenylacetaldehyde + 2 Fe(II)-[cytochrome c] + 2 H+
BioCyc:RXN-21540 1.1.2.- CPD-7035 + 2 Cytochromes-C-Oxidized --> PHENYLACETALDEHYDE + 2 Cytochromes-C-Reduced + 2 PROTON
BioCyc:RXN-13543 3.1.1.- phenylethyl acetate esterase
BioCyc:RXN-13540 2.4.1.- phenylethanol glucosyltransferase
BioCyc:RXN-11265 BENZOYLCOA + CPD-7035<=>CPD-12217 + CO-A
View More
Organism Source

Taxonomy Source

  1. Acacia aulacocarpa [ncbi taxid: 138511]
  2. Achillea nana [ncbi taxid: 282752]
  3. Aconitum fischeri [ncbi taxid: 1111064]
  4. Aconitum napellus [ncbi taxid: 112591]
  5. Actaea dahurica [ncbi taxid: 64029]
  6. Actaea heracleifolia [ncbi taxid: 64034]
  7. Actaea simplex [ncbi taxid: 64042]
  8. Actinida polygana [ncbi taxid: ]
  9. Actinidia polygama [ncbi taxid: 64480]
  10. Akebia quinata [ncbi taxid: 13331]
  11. Akebia trifoliata [ncbi taxid: 155132]
  12. Alangium premnifolium [ncbi taxid: 2918396]
  13. Aloe africana [ncbi taxid: 1080010]
  14. Aloe ferox [ncbi taxid: 117798]
  15. Aloe spicata [ncbi taxid: 992642]
  16. Aloe vera [ncbi taxid: 34199]
  17. Anemone flaccida [ncbi taxid: ]
  18. Angelica dahurica [ncbi taxid: 48101]
  19. Angelica tarokoensis [ncbi taxid: 2831630]
  20. Aphomia sociella [ncbi taxid: 688398]
  21. Apocynum androsaemifolium [ncbi taxid: 61254]
  22. Ardisia neriifolia [ncbi taxid: 2184479]
  23. Arnebia euchroma [ncbi taxid: 373122]
  24. Arnebia guttata [ncbi taxid: 419289]
  25. Artemisia argyi [ncbi taxid: 259893]
  26. Artemisia capillaris [ncbi taxid: 265783]
  27. Artemisia montana [ncbi taxid: 669134]
  28. Artemisia princeps [ncbi taxid: 223870]
  29. Aspergillus albus [ncbi taxid: ]
  30. Aspergillus fumisynnematus [ncbi taxid: 286432]
  31. Aspergillus niger [ncbi taxid: 5061]
  32. Aspidosperma subincanum [ncbi taxid: 2743209]
  33. Astragalus bisulcatus [ncbi taxid: 20406]
  34. Atractylodes lancea [ncbi taxid: 41486]
  35. Atractylodes macrocephala [ncbi taxid: 265785]
  36. Atroxima liberica [ncbi taxid: 174495]
  37. Baccharoides lasiopus [ncbi taxid: 83961]
  38. Ballota limbata [ncbi taxid: ]
  39. Bergenia crassifolia [ncbi taxid: 29762]
  40. Bidens pilosa [ncbi taxid: 42337]
  41. Bistorta manshuriensis [ncbi taxid: 1548133]
  42. Bistorta officinalis [ncbi taxid: 125587]
  43. Boenninghausenia albiflora [ncbi taxid: 452763]
  44. Bombax ceiba [ncbi taxid: 45325]
  45. Bothriocline ripensis [ncbi taxid: ]
  46. Brachyglottis bidwillii [ncbi taxid: ]
  47. Bragantia wallichii [ncbi taxid: ]
  48. Brassica hirta [ncbi taxid: ]
  49. Calea lantanoides [ncbi taxid: 3464902]
  50. Camellia saluenensis [ncbi taxid: 319929]
  51. Camptotheca acuminata [ncbi taxid: 16922]
  52. Capsella bursa-pastoris [ncbi taxid: 3719]
  53. Chaenomeles sinensis [ncbi taxid: ]
  54. Christisonia bicolor [ncbi taxid: ]
  55. Chromolaena odorata [ncbi taxid: 103745]
  56. Chroogomphus helveticus [ncbi taxid: 132909]
  57. Cibotium barometz [ncbi taxid: 29588]
  58. Cicuta virosa [ncbi taxid: 48109]
  59. Cimicifuga foetida [ncbi taxid: ]
  60. Cinnamomum verum [ncbi taxid: 128608]
  61. Citrullus lanatus [ncbi taxid: 3654]
  62. Citrus aurantifolia [ncbi taxid: ]
  63. Citrus aurantium [ncbi taxid: ]
  64. Citrus hystrix [ncbi taxid: 170989]
  65. Citrus limon [ncbi taxid: ]
  66. Citrus paradisi [ncbi taxid: ]
  67. Citrus reticulata [ncbi taxid: 85571]
  68. Citrus spp. [ncbi taxid: ]
  69. Cnidium officinale [ncbi taxid: ]
  70. Colobocentrotus atratus [ncbi taxid: 39290]
  71. Comus officinalis [ncbi taxid: ]
  72. Convallaria majalis [ncbi taxid: 32189]
  73. Conyza newii [ncbi taxid: ]
  74. Cornus officinalis [ncbi taxid: 16906]
  75. Coronilla cretica [ncbi taxid: ]
  76. Crocus sativus [ncbi taxid: 82528]
  77. Crotalaria orixensis [ncbi taxid: 1132614]
  78. Cryptocarya aschersoniana [ncbi taxid: 1345236]
  79. Dactylosporangium salmoneum [ncbi taxid: 53361]
  80. Delphinium andersoni [ncbi taxid: ]
  81. Delphinus globiceps [ncbi taxid: ]
  82. Diphasia angolensis [ncbi taxid: ]
  83. Drosera indica [ncbi taxid: 16680]
  84. Drummondita hassellii [ncbi taxid: 282608]
  85. Dysosma pleianthum [ncbi taxid: ]
  86. Elaeodendron alluaudianum [ncbi taxid: ]
  87. Enterococcus faecalis [ncbi taxid: 1351]
  88. Ephedra distachya [ncbi taxid: 3389]
  89. Epimedium davidii [ncbi taxid: 253605]
  90. Erucaria microcarpa [ncbi taxid: 1078594]
  91. Erysimum odoratum [ncbi taxid: 1137569]
  92. Espeletia grandiflora [ncbi taxid: 1933532]
  93. Eucalyptus melliodora [ncbi taxid: 183838]
  94. Eupatorium argentinum [ncbi taxid: ]
  95. Eupolyphaga sinensis [ncbi taxid: 367774]
  96. Eutypella scoparia [ncbi taxid: ]
  97. Farlowia mollis [ncbi taxid: 42016]
  98. Flindersia xanthoxyla [ncbi taxid: 67936]
  99. Flos lonicerae [ncbi taxid: ]
  100. FOOD SAKE [ncbi taxid: ]
  101. Frullania tamarisci [ncbi taxid: 95764]
  102. Galenia africana [ncbi taxid: ]
  103. Galium mollugo [ncbi taxid: 254777]
  104. Gardenia imperialis [ncbi taxid: 339298]
  105. Globba malaccensis [ncbi taxid: ]
  106. Gnidia lamprantha [ncbi taxid: ]
  107. Gomesa radicans [ncbi taxid: 587976]
  108. Grindelia scorzonerifolia [ncbi taxid: 1114760]
  109. Guatteria boliviana [ncbi taxid: 343271]
  110. Haliclona cribricutis [ncbi taxid: ]
  111. Hansenia weberbaueriana [ncbi taxid: 54724]
  112. Heracleum canescens [ncbi taxid: ]
  113. Hesperis matronalis [ncbi taxid: 264418]
  114. Heterotheca inuloides [ncbi taxid: 3015714]
  115. Homo sapiens [ncbi taxid: 9606]
  116. Homo sapiens (Skin microbiota) [ncbi taxid: ]
  117. Hyacinthus orientalis [ncbi taxid: 82025]
  118. Ilex amara [ncbi taxid: 185490]
  119. Isodon japonicus [ncbi taxid: 425908]
  120. Juglans nigra [ncbi taxid: 16719]
  121. Juniperus brevifolia [ncbi taxid: 746017]
  122. Knightia excelsa [ncbi taxid: 35944]
  123. Lagascea mollis [ncbi taxid: 1475413]
  124. Laurencia distichophylla [ncbi taxid: ]
  125. Lawsonia inermis [ncbi taxid: 141191]
  126. Leonurus glaucescens [ncbi taxid: 445399]
  127. Lepidium draba [ncbi taxid: 153317]
  128. Lepidium graminifolium [ncbi taxid: 200330]
  129. Licaria brasiliensis [ncbi taxid: ]
  130. Ligusticum elatum [ncbi taxid: ]
  131. Ligusticum sinense [ncbi taxid: ]
  132. Linum crispum [ncbi taxid: ]
  133. Lithospermum erythrorhizon [ncbi taxid: 34254]
  134. Lonchocarpus atropurpureus [ncbi taxid: 466225]
  135. Lonicera japonica [ncbi taxid: 105884]
  136. Maba buxifolia [ncbi taxid: ]
  137. Melia azedarach [ncbi taxid: 155640]
  138. Mentha x piperita [ncbi taxid: 34256]
  139. Michelia alba [ncbi taxid: ]
  140. Micromeria pineolens [ncbi taxid: 306397]
  141. Murraya paniculata [ncbi taxid: 43711]
  142. Mus striatus [ncbi taxid: ]
  143. Mycena fagetorum [ncbi taxid: 3016365]
  144. Nemalion vermiculare [ncbi taxid: 935621]
  145. Neolentinus lepideus [ncbi taxid: 38799]
  146. Nicotiana bonariensis [ncbi taxid: 118694]
  147. Nicotiana langsdorffii [ncbi taxid: 118700]
  148. Nidula candida [ncbi taxid: 1348642]
  149. Notopterygium incisum [ncbi taxid: ]
  150. Ocimum basilicum [ncbi taxid: 39350]
  151. Octopus vulgaris [ncbi taxid: 6645]
  152. Ophiocoma scolopendrina [ncbi taxid: 1365868]
  153. Pachychalina alcaloidifera [ncbi taxid: 2846801]
  154. Palafoxia texana [ncbi taxid: 176556]
  155. Penicillium citreonigrum [ncbi taxid: 69768]
  156. Peritassa compta [ncbi taxid: ]
  157. Petroselinum crispum [ncbi taxid: 4043]
  158. Petunia x hybrida [ncbi taxid: 4102]
  159. Phellinus igniarius [ncbi taxid: 40472]
  160. Phlegmariurus yunnanensis [ncbi taxid: 385391]
  161. Phyllospongia papyracea [ncbi taxid: 279625]
  162. Pinus flexilis [ncbi taxid: 151559]
  163. Pinus spp. [ncbi taxid: ]
  164. Piper longum [ncbi taxid: 49511]
  165. Pisaster giganteus [ncbi taxid: 189915]
  166. Pisolithus arhizus [ncbi taxid: 80664]
  167. Platycladus orientalis [ncbi taxid: 58046]
  168. Platytaenia lasiocarpa [ncbi taxid: ]
  169. Populus tremuloides [ncbi taxid: 3693]
  170. Pseudocinchona pachyceras [ncbi taxid: ]
  171. Psiadia dentata [ncbi taxid: 1225829]
  172. Psilotum nudum [ncbi taxid: 3240]
  173. Pulmonaria mollis [ncbi taxid: 256500]
  174. Quercus sessiliflora [ncbi taxid: ]
  175. Rabdosia angustifolia [ncbi taxid: ]
  176. Radianthus kuekenthali [ncbi taxid: ]
  177. Raputia praetermissa [ncbi taxid: 2321333]
  178. Rheedia acuminata [ncbi taxid: ]
  179. Rhodiola crenulata [ncbi taxid: 242839]
  180. Rhodiola rosea L. [ncbi taxid: ]
  181. Rhodococcus erythropolis [ncbi taxid: 1833]
  182. Rosa chinensis [ncbi taxid: 74649]
  183. Rosa rugosa [ncbi taxid: 74645]
  184. Sabadilla officinalis [ncbi taxid: ]
  185. Saccharomyces cerevisiae [ncbi taxid: 4932]
  186. Salacia madagascariensis [ncbi taxid: 670374]
  187. Sanguisorba officinalis [ncbi taxid: 137457]
  188. Saposhnikovia divaricata [ncbi taxid: 203717]
  189. Saussurea carthamoides [ncbi taxid: ]
  190. Schisandra chinensis [ncbi taxid: 50507]
  191. Scutellaria sieberi [ncbi taxid: 457167]
  192. Semen astragali complanati [ncbi taxid: ]
  193. Senegalia mellifera [ncbi taxid: 381101]
  194. Sepia officinalis [ncbi taxid: 6610]
  195. Smilax bracteata [ncbi taxid: 1045134]
  196. Solanum acaule [ncbi taxid: 103871]
  197. Spatholobus suberectus [ncbi taxid: 455371]
  198. Spodoptera eridania [ncbi taxid: 37547]
  199. Streptomyces [ncbi taxid: 1883]
  200. Streptomyces ANU 6277 [ncbi taxid: ]
  201. Streptomyces fimicarius BWL-H1 [ncbi taxid: ]
  202. Streptomyces griseovariabilis [ncbi taxid: 284636]
  203. Streptomyces parvulus [ncbi taxid: 146923]
  204. Strychnos brachiata [ncbi taxid: ]
  205. Sus scrofa [ncbi taxid: 9823]
  206. Swertia delavayi [ncbi taxid: 166617]
  207. Symphyocladia latiuscula [ncbi taxid: 396806]
  208. Tagetes minuta [ncbi taxid: 169607]
  209. Talaromyces islandicus [ncbi taxid: 28573]
  210. Teclea nobilis [ncbi taxid: ]
  211. Tenebrio obscurus [ncbi taxid: 27449]
  212. Tetracera alnifolia [ncbi taxid: ]
  213. Tetrataenium canescens [ncbi taxid: 376873]
  214. Trichoderma viride [ncbi taxid: 5547]
  215. Tricholoma acerbum [ncbi taxid: 181706]
  216. Trifolium glanduliferum [ncbi taxid: 361918]
  217. Triticum aestivum [ncbi taxid: 4565]
  218. Tynanthus panurensis [ncbi taxid: 354063]
  219. Typha latifolia [ncbi taxid: 4733]
  220. Uncaria sterrophylla [ncbi taxid: ]
  221. Vaccinium corymbosum [ncbi taxid: 69266]
  222. Vaccinium myrtillus [ncbi taxid: 180763]
  223. Vaccinium vitis-idaea [ncbi taxid: 180772]
  224. Vallota purpurea [ncbi taxid: ]
  225. Vicia amoena [ncbi taxid: 153950]
  226. Viscum articulactum [ncbi taxid: ]
  227. Vismia jefensis [ncbi taxid: ]
  228. Vitis vinifera [ncbi taxid: 29760]
  229. Xenia blumi [ncbi taxid: ]
  230. Zanthoxylum hamiltonianum [ncbi taxid: ]
  231. Zanthoxylum hamiltonium [ncbi taxid: ]

Pathway Synthetic

pathway id name
BioCyc:META_PWY-5751 phenylethanol biosynthesis
BioCyc:CAULONA1000_PWY-5751 phenylethanol biosynthesis
BioCyc:META_PWY-7114 tea aroma glycosidic precursor bioactivation
BioCyc:META_PWY-5079 L-phenylalanine degradation III
BioCyc:PLASMO_PWY-5079 phenylalanine degradation III
BioCyc:PCHR_PWY-5079 phenylalanine degradation III
BioCyc:META_PWY-7075 phenylethyl acetate biosynthesis
BioCyc:META_PWY-7074 phenylethanol glycoconjugate biosynthesis
BioCyc:YEAST_PWY-5079 phenylalanine degradation
BioCyc:SMAN_PWY-5751 phenylethanol biosynthesis
BioCyc:10403S_RAST_PWY-5751 phenylethanol biosynthesis
BioCyc:THAPS_PWY-5079 phenylalanine degradation III
BioCyc:CALBI_PWY-5079 phenylalanine degradation
BioCyc:ARA_PWY-5079 L-phenylalanine degradation III
BioCyc:MOUSE_PWY-5079 phenylalanine degradation III
BioCyc:FLY_PWY-5751 phenylethanol biosynthesis
BioCyc:THAPS_PWY-5751 phenylethanol biosynthesis
Plant Reactome:R-OAU-2744345 Metabolism and regulation
Plant Reactome:R-OAU-2744343 Amino acid metabolism
Plant Reactome:R-CME-1119267 Ehrlich pathway
View All Pathways