Phenylethyl alcohol
2-Phenylethanol, also known as benzeneethanol or benzyl carbinol, belongs to the class of organic compounds known as benzene and substituted derivatives. These are aromatic compounds containing one monocyclic ring system consisting of benzene. 2-Phenylethanol exists in all living species, ranging from bacteria to humans. 2-Phenylethanol is a bitter, floral, and honey tasting compound. 2-Phenylethanol is found, on average, in the highest concentration within a few different foods, such as red wines, black walnuts, and white wines and in a lower concentration in grape wines, sweet basils, and peppermints. 2-Phenylethanol has also been detected, but not quantified, in several different foods, such as asparagus, allspices, fruits, horned melons, and lemons. 2-Phenylethanol, with regard to humans, has been found to be associated with several diseases such as ulcerative colitis, pervasive developmental disorder not otherwise specified, and autism. 2-phenylethanol has also been linked to the inborn metabolic disorder celiac disease. A primary alcohol that is ethanol substituted by a phenyl group at position 2.
| ID | EC Number | Name |
|---|---|---|
| KEGG:R02611 | 1.1.1.90 | phenylethylalcohol:NAD+ oxidoreductase |
| Rhea:RHEA:63737 | 2-phenylacetaldehyde + NADPH + H+ => 2-phenylethanol + NADP+ | |
| Rhea:RHEA:63738 | 2-phenylethanol + NADP+ => 2-phenylacetaldehyde + NADPH + H+ | |
| Rhea:RHEA:63739 | 2-phenylacetaldehyde + NADPH + H+ <=> 2-phenylethanol + NADP+ | |
| Rhea:RHEA:63741 | 2-phenylacetaldehyde + NADH + H+ => 2-phenylethanol + NAD+ | |
| Rhea:RHEA:63742 | 2-phenylethanol + NAD+ => 2-phenylacetaldehyde + NADH + H+ | |
| Rhea:RHEA:63743 | 2-phenylacetaldehyde + NADH + H+ <=> 2-phenylethanol + NAD+ | |
| Rhea:RHEA:64837 | 2-phenylethanol + acetyl-CoA => phenethyl acetate + CoA | |
| Rhea:RHEA:64838 | phenethyl acetate + CoA => 2-phenylethanol + acetyl-CoA | |
| Rhea:RHEA:64839 | 2-phenylethanol + acetyl-CoA <=> phenethyl acetate + CoA | |
| Rhea:RHEA:64841 | 2-phenylethanol + benzoyl-CoA => phenethyl benzoate + CoA | |
| Rhea:RHEA:64842 | phenethyl benzoate + CoA => 2-phenylethanol + benzoyl-CoA | |
| Rhea:RHEA:64843 | 2-phenylethanol + benzoyl-CoA <=> phenethyl benzoate + CoA | |
| Rhea:RHEA:79320 | 2-phenylethanol + 2 Fe(III)-[cytochrome c] => 2-phenylacetaldehyde + 2 Fe(II)-[cytochrome c] + 2 H+ | |
| Rhea:RHEA:79321 | 2-phenylacetaldehyde + 2 Fe(II)-[cytochrome c] + 2 H+ => 2-phenylethanol + 2 Fe(III)-[cytochrome c] | |
| Rhea:RHEA:79322 | 2-phenylethanol + 2 Fe(III)-[cytochrome c] <=> 2-phenylacetaldehyde + 2 Fe(II)-[cytochrome c] + 2 H+ | |
| BioCyc:RXN-21540 | 1.1.2.- | CPD-7035 + 2 Cytochromes-C-Oxidized --> PHENYLACETALDEHYDE + 2 Cytochromes-C-Reduced + 2 PROTON |
| BioCyc:RXN-13543 | 3.1.1.- | phenylethyl acetate esterase |
| BioCyc:RXN-13540 | 2.4.1.- | phenylethanol glucosyltransferase |
| BioCyc:RXN-11265 | BENZOYLCOA + CPD-7035<=>CPD-12217 + CO-A | |
| BioCyc:RXN-13541 | 3.2.1.- | CPD-14528 + WATER --> CPD-7035 + Glucopyranose |
| BioCyc:RXN-7700 | 1.1.1.1 | CPD-7035 + NAD<=>PROTON + PHENYLACETALDEHYDE + NADH |
| BioCyc:RXN-13542 | 2.3.1.224 | phenylethanol acetyltransferase |
| BioCyc:RXN-13536 | 1.1.1.- | PHENYLACETALDEHYDE + NADPH + PROTON --> CPD-7035 + NADP |
| BioCyc:RXN-13694 | 3.2.1.149 | 2-phenylethyl β-primeverosidase |