N-Succinyl-2-L-amino-6-oxoheptanedioate (BioCAD00000014801)

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Metabolite Card

Formula: C11H15NO8 (289.0798)
SMILES: OC(=O)CCC(=O)N[C@@H](CCCC(=O)C(O)=O)C(O)=O

Synonyms [en]

N-Succinyl-2-L-amino-6-oxoheptanedioate; N-Succinyl-epsilon-keto-L-aminopimelic acid; N-Succinyl-2-amino-6-oxo-L-pimelic acid; N-Succinyl-L-2-amino-6-oxopimelate; (2S)-2-(3-carboxypropanamido)-6-oxoheptanedioic acid; L-2-succinylamino-6-oxoheptanedioic acid

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

N-Succinyl-2-L-amino-6-oxoheptanedioate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000014801). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

N-Succinyl-2-amino-6-ketopimelate is an intermediate in lysine biosynthesis. It is the fourth to last step in the synthesis of lysine and is converted. from tetrahydrodipicolinate via the enzyme tetrahydrodipicolinate N-succinyltransferase (EC 2.3.1.117). It is then converted to N-succinyl-L,L-2,6-diaminopimelate via the enzyme Succinyldiaminopimelate transferase (EC 2.6.1.17).

Entity Information

DBLinks

Other DBLinks
  • PubChem: 440349
  • ChEBI: ChEBI:15685
  • ChEBI: ChEBI:35266
  • HMDB: HMDB0012266
  • HMDB: HMDB12266
  • KEGG: C04462
  • RefMet: RM0043140
  • Metlin: METLIN_62901
  • Coconut NaturalProduct: CNP0359089.1

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R04365 2.3.1.117 succinyl-CoA:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
KEGG:R04475 2.6.1.17 N-succinyl-L-2,6-diaminoheptanedioate:2-oxoglutarate amino-transferase
Rhea:RHEA:11961 2.6.1.17 N-succinyl-(2S,6S)-2,6-diaminopimelate + 2-oxoglutarate => (S)-2-succinylamino-6-oxoheptanedioate + L-glutamate
Rhea:RHEA:11962 2.6.1.17 (S)-2-succinylamino-6-oxoheptanedioate + L-glutamate => N-succinyl-(2S,6S)-2,6-diaminopimelate + 2-oxoglutarate
Rhea:RHEA:11963 2.6.1.17 N-succinyl-(2S,6S)-2,6-diaminopimelate + 2-oxoglutarate <=> (S)-2-succinylamino-6-oxoheptanedioate + L-glutamate
Rhea:RHEA:17326 2.3.1.117 (S)-2,3,4,5-tetrahydrodipicolinate + succinyl-CoA + H2O => (S)-2-succinylamino-6-oxoheptanedioate + CoA
Rhea:RHEA:17327 2.3.1.117 (S)-2-succinylamino-6-oxoheptanedioate + CoA => (S)-2,3,4,5-tetrahydrodipicolinate + succinyl-CoA + H2O
Rhea:RHEA:17328 2.3.1.117 (S)-2,3,4,5-tetrahydrodipicolinate + succinyl-CoA + H2O <=> (S)-2-succinylamino-6-oxoheptanedioate + CoA
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Organism Source

Taxonomy Source

  1. Arabidopsis thaliana [ncbi taxid: 3702]

Pathway Synthetic

pathway id name
BioCyc:CAULONA1000_PWY0-781 aspartate superpathway
BioCyc:CAULONA1000_DAPLYSINESYN-PWY lysine biosynthesis I
BioCyc:CAULONA1000_P4-PWY superpathway of lysine, threonine and methionine biosynthesis I
PathBank:SMP0000794 Lysine Biosynthesis
Plant Reactome:R-OSA-2744345 Metabolism and regulation
Plant Reactome:R-OSA-2744343 Amino acid metabolism
Plant Reactome:R-OSA-1119273 Lysine biosynthesis I
Plant Reactome:R-OSA-5655122 Amino acid biosynthesis
PathBank:SMP0121266 Lysine Biosynthesis
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