EC: 3.4.21.7

plasmin ()

enzyme lambda metabolic reaction experiment
uniprot:P00747 [plasmin(Enzyme) wildtype]

D_Val_Leu_Lys_p_nitroanilide + H2O -> D_Val_Leu_Lys + 4_Nitroaniline
(( (Vmax * S) ) / (Km + S)) buffer: 137 mM NaCl, 27 mM KCl, 10 mM phosphate
PH: 7.4
Temperature: 25
uniprot:P00747 [plasmin(Enzyme) wildtype]

H2O + N_Ethoxycarbonyl_D_phenylalanyl_L_prolyl_alpha_azalysine_p_nitrophenyl_ester -> p_Nitrophenol + N_Ethoxycarbonyl_D_phenylalanyl_L_prolyl_alpha_azalysine
(( (( (kcat * E) ) * S) ) / (Km + S)) buffer:
PH: 6.2
Temperature: 21
uniprot:P06867 [plasmin(Enzyme) wildtype]

N_Ethoxycarbonyl_D_phenylalanyl_L_prolyl_alpha_azalysine_p_nitrophenyl_ester + H2O -> p_Nitrophenol + N_Ethoxycarbonyl_D_phenylalanyl_L_prolyl_alpha_azalysine
(( (( (kcat * E) ) * S) ) / (Km + S)) buffer:
PH: 6.2
Temperature: 21

Pathways

pathway id name
Reactome:R-HSA-392499 Metabolism of proteins
Reactome:R-HSA-381426 Regulation of IGF Activity by IGFBP
Reactome:R-RNO-381426 Regulation of IGF Activity by IGFBP
Reactome:R-RNO-109582 Hemostasis
Reactome:R-RNO-392499 Metabolism of proteins
Reactome:R-RNO-75205 Dissolution of Fibrin Clot
Reactome:R-HSA-109582 Hemostasis
Reactome:R-HSA-75205 Dissolution of Fibrin Clot
Reactome:R-MMU-109582 Hemostasis
Reactome:R-MMU-75205 Dissolution of Fibrin Clot
WikiPathways:WP4927 COVID-19, thrombosis and anticoagulation
PathBank:SMP0000274 Heparin Action Pathway
PathBank:SMP0000278 Lepirudin Action Pathway
PathBank:SMP0000282 Streptokinase Action Pathway
PathBank:SMP0000286 Aminocaproic Acid Action Pathway
PathBank:SMP0000269 Acenocoumarol Action Pathway
PathBank:SMP0000273 Fondaparinux Action Pathway
PathBank:SMP0000277 Bivalirudin Action Pathway
PathBank:SMP0000281 Anistreplase Action Pathway
PathBank:SMP0000285 Reteplase Action Pathway
PathBank:SMP0000268 Warfarin Action Pathway
PathBank:SMP0000656 Dicoumarol Action Pathway
PathBank:SMP0000275 Ardeparin Action Pathway
PathBank:SMP0000279 Ximelagatran Action Pathway
PathBank:SMP0000283 Tenecteplase Action Pathway
PathBank:SMP0000287 Tranexamic Acid Action Pathway
PathBank:SMP0000270 Dicumarol Action Pathway
PathBank:SMP0000586 Coagulation
PathBank:SMP0000272 Enoxaparin Action Pathway
PathBank:SMP0000276 Argatroban Action Pathway
PathBank:SMP0000280 Alteplase Action Pathway
PathBank:SMP0000284 Urokinase Action Pathway
PathBank:SMP0000288 Aprotinin Action Pathway
PathBank:SMP0000271 Phenprocoumon Action Pathway
PathBank:SMP0000655 Phenindione Action Pathway