EC: 3.1.1.2

arylesterase (aryl-ester hydrolase)

enzyme lambda metabolic reaction experiment
uniprot:P27169 [Ca2+]

H2O + Phenylacetic_acid -> Phenol + Acetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris
PH: 8
Temperature: 36
uniprot:P27169 [Ca2+]

H2O + Phenylacetic_acid -> Phenol + Acetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris
PH: 8
Temperature: 36
uniprot:P27169 [Ca2+]

Phenylacetic_acid + H2O -> Acetate + Phenol		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris
PH: 8
Temperature: 36
uniprot:P27169 [Ca2+]

H2O + Phenylacetic_acid -> Phenol + Acetate		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 50 mM Tris
PH: 8
Temperature: 36
- [arylesterase(Enzyme) wildtype]

H2O + Nafamostat -> p_Guanidinobenzoic_acid + 6_Amidino_2_naphthol		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl
PH: 7.4
Temperature: 37
- [arylesterase(Enzyme) wildtype]

Nafamostat + H2O -> p_Guanidinobenzoic_acid + 6_Amidino_2_naphthol		 (( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl
PH: 7.4
Temperature: 37
uniprot:P51647 [arylesterase(Enzyme) wildtype]

H2O + p_Nitrophenyl_acetate -> Acetate + p_Nitrophenol		 (( (V * S) ) / (Km + S)) buffer: 100 mM sodium phosphate
PH: 7.4
Temperature: 25

Pathways

pathway id name
BioCyc:MOUSE_PWY-5489 methyl parathion degradation
BioCyc:MOUSE_PWY-5490 paraoxon degradation
BioCyc:META_PWY-5148 acyl-CoA hydrolysis
BioCyc:MOUSE_PARATHION-DEGRADATION-PWY parathion degradation
BioCyc:ECOL316407_PWY-5148 acyl-CoA hydrolysis
PathBank:SMP0000817 Fatty Acid Metabolism
Reactome:R-RNO-9748784 Drug ADME
Reactome:R-HSA-9754706 Atorvastatin ADME
Reactome:R-RNO-9754706 Atorvastatin ADME
Reactome:R-MMU-9748784 Drug ADME
Reactome:R-HSA-9748784 Drug ADME
Reactome:R-MMU-9754706 Atorvastatin ADME
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-556833 Metabolism of lipids
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-556833 Metabolism of lipids
Reactome:R-RNO-8978868 Fatty acid metabolism
Reactome:R-BTA-8978868 Fatty acid metabolism
Reactome:R-HSA-556833 Metabolism of lipids
Reactome:R-HSA-8978868 Fatty acid metabolism
Reactome:R-MMU-8978868 Fatty acid metabolism
Reactome:R-RNO-2142753 Arachidonate metabolism
Reactome:R-BTA-2142688 Synthesis of 5-eicosatetraenoic acids
Reactome:R-HSA-2142688 Synthesis of 5-eicosatetraenoic acids
Reactome:R-MMU-2142688 Synthesis of 5-eicosatetraenoic acids
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-556833 Metabolism of lipids
Reactome:R-BTA-2142753 Arachidonate metabolism
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-2142753 Arachidonate metabolism
Reactome:R-MMU-2142753 Arachidonate metabolism
Reactome:R-RNO-2142688 Synthesis of 5-eicosatetraenoic acids
WikiPathways:WP4157 GABA metabolism (aka GHB)
PathBank:SMP0000610 Clopidogrel Metabolism Pathway
PathBank:SMP0000260 Clopidogrel Action Pathway