Atorvastatin ADME
Liu YM, Pu HH, Liu GY, Jia JY, Weng LP, Xu RJ, Li GX, Wang W, Zhang MQ, Lu C, Yu C. Pharmacokinetics and bioequivalence evaluation of two different atorvastatin calcium 10-mg tablets: A single-dose, randomized-sequence, open-label, two-period crossover study in healthy fasted Chinese adult males. Clin Ther. 2010 Jul;32(7):1396–407. doi: 10.1016/j.clinthera.2010.07.004. PMID: 20678686.; Kalliokoski A, Niemi M: Impact of OATP transporters on pharmacokinetics. Br J Pharmacol. 2009 Oct;158(3):693-705. doi: 10.1111/j.1476-5381.2009.00430.x. Epub 2009 Sep 25.; Schachter M. Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update. Fundam Clin Pharmacol. 2005 Feb;19(1):117–25. doi: 10.1111/j.1472-8206.2004.00299.x. PMID: 15660968.; Lennernäs H. Clinical pharmacokinetics of atorvastatin. Clin Pharmacokinet. 2003;42(13):1141–60. doi: 10.2165/00003088-200342130-00005. PMID: 14531725.; Garcia MJ, Reinoso RF, Sanchez Navarro A, Prous JR. Clinical pharmacokinetics of statins. Methods Find Exp Clin Pharmacol. 2003;25(6):455. doi: 10.1358/mf.2003.25.6.769652.; Malhotra HS, Goa KL. Atorvastatin: an updated review of its pharmacological properties and use in dyslipidaemia. Drugs. 2001;61(12):1835–81. doi: 10.2165/00003495-200161120-00012. PMID: 11693468.